(6) The organism is found in the mouths of most healthy dogs (74 percent) and cats (57 percent), but can cause lethal infections in up to about 30 percent of cases when individuals are asplenic
, heavy users of alcohol or otherwise immunocompromised.6 A lick on a scratch by his puppy nearly cost a young WI boy his life--he lost his fingers and toes to C.
canimorsus remains a major cause of septicemia in persons, particularly those who are asplenic
or immunocompromised, who are bitten by dogs or cats.
Capnocytophaga canimorsus is commonly transmitted by dog bites and is usually life-threatening to people who suffer from alcoholism or are asplenic
, meaning their spleens dont function normally.
These are DNA remnants seen in asplenic
or hyposplenic patients (6).
Hyposplenic or asplenic
patients are at risk of contracting an overwhelming postsplenectomy infection (OPSI) and as such should receive additional vaccination .
The 2014 guidelines for diagnosis and management of skin and soft tissue infections recommend an antibiotic prophylaxis for infections due to dog or cat bites for patients who are immunocompromised, asplenic
, or with advanced liver disease; an antimicrobial therapy is also recommended when there is an important local reaction in the site of bite or when the injuries are moderate to severe.
reported that 33% of septicaemia occurs in asplenic
He is functionally asplenic
and will need to take prophylactic antibiotics the rest of his life to prevent and protect against sepsis, a huge risk of death for our kids in the heterotaxy community," she added.
Falagas, "Vaccination of asplenic
or hyposplenic adults," British Journal of Surgery, vol.
In contrast to meningococcemia patients with pneumococcal induced purpura fulminans are often not hypotensive and 51% to 63% are asplenic
Correction of hypercoagulability and amelioration of pulmonary arterial hypertension by chronic blood transfusion in an asplenic
haemoglobin E/beta-thalassemia patient.
& immunocompromised patients are at higher risk.