Since then, it has been related to other invasive diseases, especially in asplenic
and immunosuppressed patients and in healthy people with pertussis-like symptoms (4).
He is functionally asplenic
and will need to take prophylactic antibiotics the rest of his life to prevent and protect against sepsis, a huge risk of death for our kids in the heterotaxy community," she added.
Correction of hypercoagulability and amelioration of pulmonary arterial hypertension by chronic blood transfusion in an asplenic
haemoglobin E/beta-thalassemia patient.
& immunocompromised patients are at higher risk.
Immunizations for pneumococcal disease, Haemophilus influenzae type b infection, and meningococcal disease are recommended for asplenic
During 2 vaccination days (February 8 and 11), the first of 3 doses of MenB-FHbp was offered to eligible persons affiliated with Providence College: 1) all undergraduate students; 2) graduate students or staff aged <25 years who lived or worked on campus, 3) persons in an intimate physical relationship with an undergraduate, and 4) asplenic
persons or persons with an immunocompromising condition known to place them at risk for meningococcal disease.
Four deaths may have been directly related to the splenectomy: 3 were secondary to sepsis (being asplenic
may have contributed to excess mortality risk from sepsis) and 1 from a cerebrovascular accident which may have been attributable to rebound thrombocytosis (this patient's platelet count was 1 214 x [10.
patients and in patients in whom the spleen is dysfunctional, especially bacteriae with polysaccharide capsule cause to severe infections with a high mortality rate.
Overwhelming infection in asplenic
patients: current best practice preventive measures are not being followed.
Those with polysplenia typically are associated with hyparterial pulmonary bronchi, while asplenic
patients usually have eparterial bronchi.
MenACWY-CRM can be given with pneumococcal conjugate vaccine 13 in children, including those who are asplenic
7,8 The commonly used pneumococcal polysaccharide vaccine is ineffective in asplenic
subjects, because it requires the presence of IgM memory B cells, and should be given before splenectomy.