The committee voted unanimously in favor of a booster dose of MenB vaccine 1 year after completion of the primary series, with additional boosters every 2-3 years "for as long as risk remains" for high-risk persons, including microbiologists and persons with complement deficiency, complement inhibitor use, or asplenia
. The committee also voted unanimously in favor of a one-time MenB booster for individuals aged 10 years and older who are at least a year beyond completion of a MenB primary series and deemed at increased risk by public health officials in an outbreak situation.
LAIV is an option for adults aged <49 years, except those who 1) have immunocompromising conditions, including human immunodeficiency virus (HIV) infection; 2) have anatomic or functional asplenia
; 3) are pregnant; 4) have close contact with or are caregivers of severely immunocompromised persons in a protected environment; 5) have received influenza antiviral medications in the previous 48 hours; or 6) have a cerebrospinal fluid leak or a cochlear implant.
Los pacientes que la padecen suelen sufrir de hemolisis cronica (dada por la deformidad de los globulos rojos), asplenia
funcional y crisis episodicas de dolor desencadenadas por eventos vaso-oclusivos .
" Meningococcal vaccination guidelines also underwent several small changes pertaining to adults with anatomical or functional asplenia
and human immunodeficiency virus, among other risk factors.
syndrome is frequently complicated by total anomalous pulmonary venous connection (TAPVC).
Other risk factors for invasive pneumococcal infections include extremes of age; diabetes mellitus; chronic renal insufficiency; chronic liver disease; chronic pulmonary disease; anatomical or functional asplenia
; tobacco abuse; certain ethnic groups, such as Alaskan natives; and other immunosuppressive conditions, such as HIV and multiple myeloma.
This is seen in association with wandering spleen or congenital asplenia
. This type presents with chronic or intermittent symptoms.
Of the patients that are symptomatic from babesiosis, the majority are elderly or immunocompromised, either with a concurrent infection such as HIV, have a malignancy, are being treated with immunosuppressive therapy, or are asplenia
(1,5) The manifestations of symptomatic babesiosis in immunocompromised patients are generally similar to those of immunocompetent patients; however, these individuals are also at risk for severe Babesia complications including a prolonged and relapsing course, respiratory failure, DIC, congestive heart failure, renal and liver failure, or death.
as right atrial isomerism known with cardiovascular or asplenia
it is a congenital Babies anomalies, are condition.
(7) Functional asplenia
has been reported and is defined as impaired splenic reticulo-endothelial function in spite of splenic enlargement.
Familial isolated congenital asplenia
: case report and literature review.
Risk factors for DRSP infection include comorbidities such as diabetes mellitus or chronic heart, liver, lung or renal disease; alcoholism; malignancy; asplenia
; immune-compromised conditions including the use of immunosuppressant drugs; and use of antimicrobials in the past three months.