aspiration biopsy

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Related to aspiration biopsy: aspiration cytology


removal and examination, usually microscopic, of tissue from the living body, often to determine whether a tumor is malignant or benign; biopsies are also done for diagnosis of disease processes such as infections.
Technique for endometrial biopsy. Longitudinal strips of the endometrium are sampled using an in-and-out and rotational motion. From Rakel, 2000.
aspiration biopsy one in which tissue is obtained by application of suction through a needle attached to a syringe.
brush biopsy one in which the sample is obtained by a brush with stiff bristles introduced through an endoscope, such as for a tissue sample from an inaccessible place such as the renal pelvis or bronchus.
chorionic villus biopsy chorionic villus sampling.
cone biopsy one in which an inverted cone of tissue is excised, as from the uterine cervix.
endoscopic biopsy removal of tissue by instruments inserted through an endoscope.
excisional biopsy removal of biopsy tissue by surgical cutting, such as a lumpectomy.
fine-needle aspiration biopsy aspiration biopsy using a fine needle. For superficial tissue such as the thyroid, breast, or prostate the needle is unguided, but for deep tissue it must be guided radiologically.
incisional biopsy biopsy of a selected portion of a lesion.
needle biopsy (percutaneous biopsy) one in which tissue is obtained by insertion through the skin of a special type of needle (see biopsy needle).
punch biopsy one in which tissue is obtained by a punch-type instrument.
sentinel node biopsy biopsy of a sentinel node (the first lymph node to receive lymphatic drainage from a malignant tumor). It is identified as follows: a dye and a radioactive substance are injected into the body, which causes certain nodes to “light up” like a sentinel, indicating that they are the most appropriate ones for examination. They are detected by both the light created by the dye and the radioactive substance that is monitored by a gamma camera. If the sentinel nodes do not contain malignant cells, this usually eliminates the need for removal of more distal nodes. Called also intraoperative lymphatic mapping.
shave biopsy biopsy of a skin lesion by excising it with a cut parallel to the surface of the surrounding skin.
stereotactic biopsy biopsy of the brain using a stereotactic technique to locate the biopsy site. This can be done as a minimally invasive surgery technique. The patient's head is held in a special rigid frame so that a probe can be directed into the brain through a small hole in the skull.
sternal biopsy biopsy of bone marrow of the sternum removed by puncture or trephining; see also sternal puncture.

nee·dle bi·op·sy

any method in which the specimen for biopsy is removed by aspirating it through an appropriate needle or trocar that pierces the skin, or the external surface of an organ, and into the underlying tissue to be examined.
Synonym(s): aspiration biopsy

aspiration biopsy

the removal of living tissue, for microscopic examination, by suction through a fine needle attached to a syringe. The procedure is used primarily to obtain cells from a lesion containing fluid or when fluid is formed in a serous cavity. See also cytology, needle biopsy.

aspiration biopsy

Fine-needle aspiration biopsy, see there.

nee·dle bi·op·sy

(nē'dĕl bī'op-sē)
Any method in which the specimen for biopsy is removed by aspirating it through an appropriate needle or trocar that pierces the skin, or the external surface of an organ.
Synonym(s): aspiration biopsy.


(bi'op?se) [ bio- + -opsy],


A tissue sample removed from the body for microscopic examination, usually to establish a diagnosis. The tissue can be obtained surgically or by aspiration. The procedure can be guided by computed tomography, ultrasonography, magnetic resonance imaging, or radiography, or it can be performed without imaging, i.e., “blindly”.

aspiration biopsy

Needle biopsy.

blind biopsy

A biopsy taken without radiographic guidance or strong evidence of localized disease.

brush biopsy

The removal of cells from an organ by rubbing them loose.

cone biopsy

Removal of a cone shaped piece of tissue from the uterine cervix to diagnose or treat cervical diseases. The procedure may be performed with a scalpel, carbon dioxide (CO2) laser, or Loop Electrosurgical Excision Procedure (LEEP).

endometrial biopsy

The removal of a sample of uterine endometrium for microscopic study. The procedure is commonly used in fertility assessment to confirm ovulation and to determine the cause of dysfunctional or postmenopausal bleeding.
Enlarge picture

fine needle aspiration biopsy

Abbreviation: FNA biopsy
The removal of cells or tissue through a long, narrow-gauge needle with or without radiological guidance.
See: illustration

fine-needle nonaspiration biopsy

Fine-needle capillary sampling.

liver biopsy

1. The percutaneous removal of tissue from the liver with a large-bore needle that captures a core of tissue.
2. A wedge of the liver obtained during laparotomy or laparoscopy.

muscle biopsy

The removal of muscle tissue for microscopic examination and chemical analysis.

needle biopsy

The withdrawal of fluid or tissue by means of negative pressure applied with needle and syringe.
Synonym: aspiration biopsy

percutaneous breast biopsy

Use of a directional, high-speed, rotating cutter attached to a vacuum source to gather multiple contiguous core samples of breast tissue through a single point of insertion. This minimally invasive procedure is usually performed under local anesthesia, using stereotactic imaging or real-time ultrasonography.

percutaneous renal biopsy

Obtaining renal tissue for analysis with a needle inserted through the skin, usually done after the kidney has been localized by ultrasound, computed tomography, or angiography. This technique is used to establish a diagnosis of renal dysfunction, determine prognosis in patients with renal disease, evaluate the extent of renal injury, and determine appropriate therapy. The most common complication is urinary bleeding, which tends to clear gradually over several days.

percutaneous transthoracic needle aspiration biopsy

Use of a radiographically guided aspiration needle to obtain a sample of tissue in cases of suspected pulmonary malignancies or other unknown lesions. Because of the risk of pneumothorax, the procedure is usually contraindicated in patients receiving mechanical ventilation.

punch biopsy

The removal of a small piece of tissue (usually of the skin) with a hollow, round cutting tool.

sentinel node biopsy

A technique for identifying the initial site of cancer metastasis. After injection of a radioactive tracer directly into the tumor mass, the tissue is massaged to encourage uptake of tracer by lymphatic vessels. A negative biopsy of the first node infiltrated by the tracer suggests that the malignancy has not yet spread to neighboring regional lymph nodes.

shave biopsy

Removal of a shallow layer of skin with a cutting instrument, e.g., a scalpel, sawing parallel to the skin surface. A shave biopsy may leave a small depression in the skin.


It should not be used to remove lesions suspected for melanoma or lesions that seem to have significant depth.

suction biopsy

A technique for obtaining tissue by aspiration, e.g., to obtain tissue from the mucosa of the stomach and intestines.

vacuum-assisted biopsy

A biopsy technique in which a hypodermic probe is placed through the skin into an organ of the body (such as the breast), and negative pressure is used to draw one or more samples into a chamber, where they are captured and removed for analysis under a microscope.

Aspiration biopsy

The removal of cells in fluid or tissue from a mass or cyst using a needle for microscopic examination and diagnosis.
Mentioned in: Breast Cancer

nee·dle bi·op·sy

(nē'dĕl bī'op-sē)
Method in which the specimen for biopsy is removed by aspirating it through an appropriate needle or trocar that pierces the skin.
Synonym(s): aspiration biopsy.


1. the act of inhaling. Pathological aspiration of vomitus or mucus into the respiratory tract may occur when a patient is unconscious or under the effects of a general anesthetic.
2. removal of fluids or gases from a cavity by the aid of suction.

aspiration biopsy
see biopsy.
aspiration pneumonia
is the result of inhalation or aspiration of infected solid or liquid material into the lungs. Large volumes of aspirate cause asphyxia, smaller amounts cause a necrotic or gangrenous pneumonia, in anterior and ventral parts of the lung. There is profound toxemia, cough, gurgling or squeaky rales, and usually an attendant pleurisy producing a friction rub. Called also inhalation pneumonia.


removal and examination, usually microscopic, of tissue from the living body. Biopsies are usually done to determine whether a tumor is malignant or benign; however, a biopsy may be a useful diagnostic aid in other disease processes such as infections.

aspiration biopsy
biopsy in which tissue is obtained by application of suction through a needle attached to a syringe.
bite biopsy
instrumental removal of a fragment of tissue.
bone marrow biopsy
obtaining a sample of bone marrow, usually by needle aspiration, from a long bone, rib or sternum, for cytological examination.
Enlarge picture
Needle aspiration of bone marrow. By permission from Ettinger SJ, Feldman E, Textbook of Veterinary Internal Medicine, Saunders, 2004
brush biopsy
removal of cells and tissue fragments using a brush with stiff bristles (introduced through an endoscope). Effective in obtaining tissue samples from inaccessible places such as the renal pelvis.
closed biopsy
one carried out without access through an open incision such as a laparotomy. An example is a percutaneous, fine needle aspirate.
cone biopsy
biopsy in which an inverted cone of tissue is excised, as from the uterine cervix.
cytological biopsy
obtaining specimens of cells by various methods including irrigation of a hollow tube.
biopsy dart
an alternative to immobilization of large and wild animals; a dart which cuts a skin bipsy, then falls out. Limited to use for superficial lesions.
endoscopic biopsy
removal of tissue by appropriate instruments through an endoscope.
excisional biopsy
biopsy of tissue removed from the body by surgical cutting.
exploratory biopsy
a combination of exploratory surgery to determine size and location of a lesion and the taking of a biopsy.
fine needle biopsy
see needle biopsy (below).
hepatic biopsy
may be by transperitoneal incision, more commonly by percutaneous needle or trocar and cannula technique.
incisional biopsy
biopsy of a selected portion of a lesion.
needle biopsy
biopsy in which tissue is obtained by puncture of a tumor, the tissue within the lumen of the needle being detached by rotation, and the needle withdrawn.
punch biopsy
see punch biopsy.
Robson-Heggers biopsy
a procedure for the collection of a piece of tissue from an infected wound in order to determine the extent and the nature of the infection.
sternal biopsy
biopsy of bone marrow of the sternum removed by puncture or trephining (see also sternal puncture).
surface biopsy
sample of cells scraped from the surface of a lesion or obtained by impression smears.
surgical biopsy
one obtained during a surgical procedure.
synovial biopsy
by a needle biopsy technique or through an arthrotomy incision using special forceps for a bite biopsy.
total biopsy
obtained by removal of the entire lesion. May be for therapeutic as well as diagnostic purposes.
ultrasound-guided biopsy
use of ultrasonography to guide the passage of a needle or biopsy instrument into an internal organ or lesion.
References in periodicals archive ?
The impact of assessing specimen adequacy and number of needle passes for fine-needle aspiration biopsy of thyroid nodules.
Why our patient sustained a strong and precocious progression of the infection into the IVD and adjacent vertebral body after a CT-guided aspiration biopsy of the vertebral body is somewhat an enigma.
Sipos, "Should all patients with subcentimeter thyroid nodules undergo fine-needle aspiration biopsy and preoperative neck ultrasonography to define the extent of tumor invasion?
Ultrasound-guided fine-needle aspiration biopsy in unselected consecutive patients with thyroid nodules.
Accuracy of fine-needle aspiration biopsy in the diagnosis of well-differentiated thyroid carcinoma Cancer type Cytological findings Definite Suspicious for Benign/ malignancy, malignancy, indeterminate, n (%) n (%) n (%) Papillary (n = 56) 22 (39.
CT-guided transthoracic needle aspiration biopsy of pulmonary nodules: Needle size and pneumothorax rate.
Material and Method: Between May 2003 and June 2009, fine-needle aspiration biopsy was performed in 14 patients with an intraocular tumor.
Fine needle aspiration biopsy in the oral cavity and head and neck region.
Fine needle aspiration biopsy revealed abundant cystic fluid.
Fine needle aspiration biopsy of thyroid nodules advantages, limitations and effects.