Insights into the selective inhibition of Candida albicans Secreted
Aspartyl Protease: A docking analysis study.
aspS encoding an unusual
aspartyl protease from Sclerotinia sclerotiorum is expressed during phytopathogenesis.
Succinimide formation from
aspartyl and asparaginyl peptides as a model for the spontaneous degradation of proteins.
Candida albicans secreted
aspartyl proteinases in virulence and pathogenesis.
Biochemical characterization of
aspartyl phosphate phosphatase interaction with a phosphorylated response regulator and its inhibition by a pentapeptide.
(2016) The
aspartyl protease DDI2 activates Nrf1 to compensate for proteasome dysfunction.
The most numerous are cysteine cathepsins (B, H, L), and there are also
aspartyl cathepsins (D, E) but these are less numerous.
The HIV-1 protease is a retroviral
aspartyl protease that is essential for the life cycle of HIV, the retrovirus that causes AIDS [13].
Henriques, "Candida tropicalis Biofilms: Biomass, Metabolic Activity and Secreted
Aspartyl Proteinase Production," Mycopathologia, vol.
Aspartic proteinases (EC 3.4.23) or
aspartyl proteinases are endopeptidases having two aspartic acid residues (Asp32 and Asp215, pepsin numbering) within their active site that are vital for their catalytic activity [7].
Renin is an
aspartyl protease glycoprotein enzyme that catalyses the restrictive excision of the angiotensinogen (AGT) to angiotensin I (Ang I), an essential component within the processes of the system's activation [8].
Morgenstern et al., "A radiolabeled fully human antibody to human
aspartyl (asparaginyl) jhydroxylase is a promising agent for imaging and therapy of metastatic breast cancer," Cancer Biotherapy & Radiopharmaceuticals, vol.