aspartate transaminase

Also found in: Dictionary, Encyclopedia, Wikipedia.
Related to aspartate transaminase: Alanine transaminase

aspartate transaminase

 (AST) (ASAT) [ah-spahr´tāt trans-am´ĭ-nās]
an enzyme that catalyzes the reversible transfer of an amino group from aspartate to α-ketoglutarate to form glutamate and oxaloacetate, requiring the coenzyme pyridoxal phosphate; it is normally present in serum and in various body tissues, especially in the heart and liver. (See accompanying table.) It is released into the serum as the result of tissue injury, especially injury to the heart or liver, hence the concentration in the serum may be increased in myocardial infarction or acute damage to hepatic cells. Serum levels are also increased in some muscle diseases, such as progressive muscular dystrophy. Called also glutamic-oxaloacetic transaminase.

as·par·tate a·mi·no·trans·fer·ase (AST),

an enzyme catalyzing the reversible transfer of an amine group from l-glutamate to oxaloacetate, forming α-ketoglutarate and l-aspartate; an aid in diagnosing viral hepatitis and myocardial infarction.

aspartate transaminase

/as·par·tate trans·am·i·nase/ (AST) (ASAT) (trans-am´ĭ-nās) an enzyme normally present in body tissues, especially in the heart and liver; it is released into the serum as the result of tissue injury, hence the concentration in the serum (SGOT) may be increased in disorders such as myocardial infarction or acute damage to hepatic cells.

aspartate transaminase


Asp; any salt of aspartic acid; aspartic acid in dissociated form.

aspartate carbamoyl transferase
enzyme catalyzing the condensation of carbamoyl phosphate and l-aspartate to N-carbamoyl-l-aspartate. A regulatory, allosteric enzyme in the synthesis of pyrimidine nucleotides.
aspartate transaminase

Patient discussion about aspartate transaminase

Q. I got advice from my friend who did try this and succeeded. This is Liam, 26, male. Can I try diet pills to gain shape in a short period of time. I got advice from my friend who did try this and succeeded.

A. Hi Liam, I don’t have any interest in diet pills and don't believe that. Try lots of exercise which you like, such as running, swimming. And eat healthy!!!! Don't diet and eat less just eat healthier foods. Stay far away from fast food. Eat healthy and feel healthy!

Q. What is the risk of biabetes if my father got it? My father was recently diagnosed at the age of 55 as having Type 2 Diabetes. Do I have a greater risk of developing diabetes also?

A. Indeed, as a first degree relative of a diabetic patient you have a higher risk of developing diabetes than the average person. The risk of developing diabetes depends on many factors, both genetic and non-genetic (nutrition, weight and exercise). The risk also depends on other relevant conditions you may have (for example hypertension, elevated blood cholesterol or lipid levels).
It should be mentioned, that even for an individual whose parents both have type 2 diabetes, the risk of developing type 2 diabetes isn’t 100% but rather less than 50%.

Q. what do i do if i got the flu? how do i treat it right????

A. if you got the Flu - the best way to treat it is just staying at home, drinking a lot of fluids eating well and waiting until it's over. it's a virus infection and there is no effective medication for it (there's Tamiflu- but it helps only in the first few days and have side effects that just not worth it. worse then the disease.).
it'll take a week probably of sitting at home watching T.V , reading and such- not that bad. but if you will have a very high fever- you can take any non prescriptional drug that the pharmacist will advise to lower it.

More discussions about aspartate transaminase
References in periodicals archive ?
Evaluations of activities of enzymes (acid and alkaline phosphatases, alanine and aspartate transaminases, lactate, and glucose-6-phosphate dehydrogenases) were carried out in the samples collected.
jugularis on day 0, 30 and 45 for the analysis of triglyceride, total cholesterol, glucose, aspartate transaminase (AST), alkaline phosphatase (ALP), lactate dehydrogenase (LDH), creatine kinase (CK), gamma-glutamyl transpeptidase (GGT), total protein (TP), albumin (ALB), globulin (GLOB), creatinine (CREA), blood urea nitrogene (BUN), calcium (Ca), magnesium (Mg), phosphorus (P), sodium (Na), potassium (K), chlor (Cl), lactic acid (LA).
Serum was collected and separated to measure alanine transaminase (ALT), aspartate transaminase (AST) and lactate dehydrogenase (LDH) enzymatic activity.
On her third day in the ICU, the patient still had pancytopenia and elevated concentrations of aspartate transaminase (674 IU/L) and alanine transaminase (105 IU/L).
Additional laboratory markers such as creatine kinase (CK), lactate dehydrogenase (LDH), aspartate transaminase (AST) and alanine transaminase (ALT) were elevated in five patients.
Aspartate transaminase catalyzes the interconverssion of aspartate and a-Ketoglutarate to oxaloacetate and glutamate.
Bilirubin, Aspartate transaminase, Alanine transaminase, total and differential proteins, was all normal.
Liver function tests were unremarkable with the exception of low albumin of 33 g/l and mildly elevated aspartate transaminase of 46 U/l.
Patients with alanine transaminase (ALT) or aspartate transaminase (AST) [greater than or equal to] 40 U/L were excluded to avoid including higher degree of liver injury, non-alcoholic "steatohepatitis" (NASH) and other causes of hepatitides.
05) increase in the serum concentrations of aspartate transaminase (AST), alanine transaminase (ALT), and alkaline phosphatase (ALP) of animals treated with the extract of E.
Blood samples was drawn to determination the serum values of Aspartate Transaminase (AST), Alanine Transaminase (ALT), Uric Acid, Alkaline phosphatase (ALP), and Creatinine.
His low-density lipoprotein cholesterol (LDL-C) is 130 mg/dL; triglycerides, 300 mg/dL; alanine transaminase (ALT), 110 units/L; and aspartate transaminase (AST), 120 units/L.