asparaginyl

as·pa·rag·i·nyl (N, N),

(as-par'ă-jin-il),
The aminoacyl radical of asparagine.
References in periodicals archive ?
Deamidation of glutaminyl and asparaginyl residues in peptides and proteins.
Objective: This project entitled Synthesis of Truncated tirandamycin A-D derivatives as new Antihelminthic Agents (STTDAA) aims at developing novel asparaginyl tRNA synthetase (AsnRS) inhibitors as potential antihelminthic agents, with new mechanisms of action for potential treatment of lymphatic filariasis (LF).
Proteomics-based identification of novel factor inhibiting hypoxia-inducible factor (FIH) substrates indicates widespread asparaginyl hydroxylation of ankyrin repeat domain-containing proteins.
Regulation of hypoxia-inducible factor 1 by prolyl and asparaginyl hydroxylases.
Stability of adrenocorticotropic hormone (ACTH) and pathways of deamidation of asparaginyl residue in hexapeptide segments.
Clarke, Deamidation, isomerization, and racemization at asparaginyl and aspartyl residues in peptides.
The hydroxylation is catalyzed by a variety of nonheme iron-containing dioxygenases, including prolyl, asparaginyl, and lysyl hydroxylases (Hewitson et al.
Among them are two long-known collagen prolyl-4-hydroxylases (Myllyharju 2003), the more recently identified FIH-1 (factor inhibiting HIF), and PHD1-3, asparaginyl and prolyl hydroxylases, responsible for HIF-[alpha] protein hydroxylation (Epstein et al.
The stability and degradation pathway of recombinant human parathyroid hormone: deamidation of asparaginyl residue and peptide bond cleavage at aspartyl and asparaginyl residues.
9-Da marker peptide appeared in the Hb variant [[beta]66 Lys[right arrow]Asn] only, but not in wild-type Hb, and was confirmed to be an amino acid substitution by elimination of the tryptic cleavage site at Lys([beta]66) and by the characteristic mass increase of 114 Da, which indicated the addition of an asparaginyl residue to this position.
Structure of the EF corner favors deamidation of asparaginyl residues in hemoglobin: the example of Hb La Roche-sur-Yon [[beta]81(EF5)Leu [right arrow] His].

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