artesunate


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artesunate

(ahr-tez'ŭ-nāt),
A derivative of artemisinin, an antimalarial.

artesunate

A drug used to treat difficult cases of Falciparum malaria. A study published in August 2005 showed that artesunate was a more effective drug than quinine for the treatment of Falciparum malaria. The drug is on the WHO official list.
References in periodicals archive ?
It was noted that 12 (24%) patients received artesunate and 16 (32%) patients received quinine only.
30/32 (93.75%) of the parenteral anti -malarial used was intravenous quinine.2 (6.25%) had intramuscular artemether and none had intravenous artesunate. The range of duration of stay in the ward was between 2 to 6 days with mean of 3.84 days .All except one child recovered with treatment.
Scientists at St George's, University of London, and St George's Hospital, are in the second phase of research into whether the malaria drug artesunate, can have a positive effect on colorectal cancer patients by reducing the multiplication of tumor cells and decreasing the risk of cancer spreading or recurring after surgery.
ActRx Triact, a twoday regimen against dengue, is comprised of an artemether sublingual spray and artesunate and berberine tablets.
Daily administration of artesunate to rats for 5 days caused no significant changes in the number of abnormal sperm compared with the controls.
There were also certain drugs that showed a runaway price rise, including anti- malarial drug Artesunate ( 31 per cent price rise), antihypertensive Olmesartan+ HCTZ ( 31 per cent price increase) and Levothyroxine ( 34 per cent price hike).
The new treatment, combining pyronaridine and artesunate, was tested at seven sites in Africa and three in Southeast Asia alongside the standard drugs, artemether and lumefantrine, BBC reported.
The new strain is especially resistant to artesunate drugs, one of the world's most common treatment for malaria.
In addition to making arrests, Chinese police seized 24,000 packets of counterfeit artesunate pills.
(5) Other drugs, such as atovaquone/proguanil and artesunate, are not well studied in pregnancy, and therefore are not recommended for use unless other options are not available.
The Drugs for Neglected Diseases Initiative in March announced that ASAQ, a fixed-dose combination of artesunate and amodiaquine, will soon be available throughout the area where the majority of the deadly malaria cases hit.