arterial nephrosclerosis

(redirected from arterionephrosclerosis)

ar·te·ri·al neph·ro·scle·ro·sis

patchy atrophic scarring of the kidney caused by arteriosclerotic narrowing of the lumens of large branches of the renal artery, occurring in old or hypertensive persons and occasionally causing hypertension.

arteriolar nephrosclerosis

A destructive form of atherosclerosis involving the renal arteries secondary to severe–malignant (renovascular) hypertension which, if prolonged, leads to renal failure.
Histologic patterns
• Hyaline arteriolosclerosis, in which there is homogeneous pink hyaline thickening of the arteriolar walls, is associated with benign nephrosclerosis.
• Fibrinoid necrosis of arterioles accompanied by an inflammatory infiltrate resulting in necrotising alveolitis and hyperplastic arteriolitis, with onionskin-like layering of fibroblasts, smooth muscle cells, and collagen.
• Hyperplastic arteriolosclerosis, with a concentric thickening with progressive narrowing of the lumina, may be associated with malignant hypertension, nephrosclerosis, and scleroderma.

ar·te·ri·al neph·ro·scler·o·sis

(ahr-tēr'ē-ăl nef'rō-skler-ō'sis)
Patchy atrophic scarring of the kidney due to arteriosclerotic narrowing of the lumens of large branches of the renal artery, occurring in old or hypertensive people and occasionally causing hypertension.
Synonym(s): arterionephrosclerosis.
References in periodicals archive ?
Rethinking hypertensive kidney disease: arterionephrosclerosis as a genetic, metabolic, and inflammatory disorder.
Microscopically, the kidneys showed a diffuse lymphoplasmacytic infiltrate with eosinophils and exuberant fibrosis, as well as arterionephrosclerosis and arteriolonephrosclerosis.
Benign arterionephrosclerosis occurring in hypertensive patients leads to a mild to moderate increase in serum creatinine (2, 3).
(1988) suggested that diets high in fat lead to arterionephrosclerosis, which in combination with cholesterol deposits in the renal tubules may enhance the development of renal cancer.
Different renal lesions have been reported in patients with HIV infection, including: idiopathic (non-HIVAN) focal and segmental glomerulosclerosis, arterionephrosclerosis, hemolytic uremic syndrome/thrombotic thrombocytopenic purpura (HUS/TTP, allergic interstitial nephritis, chronic interstitial nephritis from Amphotericin B, immunoglobulin A nephropathy, immunodactoid glomerulonephritis, renal amyloidosis, membranoproliferative glomerulonephritis, and membranous glomerulonephritis (Betjes et al., 2001; Cohen & Nast, 1988; Cosgrove, Abu-Alfa, & Perazella, 2002; Pardo et al., 1987; Rao et al., 1987; Szczech, 2001).
insipidus, immunotactoid glomerulonephritis, renal amyloidosis, systemic lupus erythematous, Henoch-Schonlein purpura, malignancy, vascular disorders, arterionephrosclerosis, HUS/TTP, allergic interstitial nephritis, membranoproliferative glomerulonephritis, membranous glomerulonephritis, nephritic wasting syndrome, FSGS, IgA nephropathy, glomerulonephritis, Wegener's granulomatosis, cystitis, scleroderma, Goodpasture's disease, nephrotic syndrome, acute tubular necrosis, pyelonephritis, and chronic renal failure.
(23,24) Arterionephrosclerosis (or hypertensive nephropathy) and diabetic nephropathy are seen in approximately 30% and 20% of cases, respectively.
Arterionephrosclerosis (also called hypertensive nephropathy/nephrosclerosis) is the most common finding in adult tumor nephrectomy specimens.
The pathologic diagnosis of arterionephrosclerosis is based on a constellation of nonspecific histopathologic features.
There are no pathognomonic histopathologic features for arterionephrosclerosis. In the absence of an immune complex-mediated injury, the combination of global glomerulosclerosis, interstitial fibrosis and tubular atrophy, and arteriosclerosis is consistent with this diagnosis.
Chronic Renal Failure * 1 61/M 60 Polycystic kidney disease 2 36/F 48 IgA PVAN 3 57/M 60 Polycystic kidney disease 4 58/M 36 Unknown 5 53/F 48 Arterionephrosclerosis 6 41/M 24 Nephroangiosclerosis 7 65/M 12 Glomerular disease 8 38/F 12 IgA PVAN * IgA indicates immunoglobulin A.