EXAMPLE 1, SAMPLE AUTOPSY SIGNOUT: * Cerebral age-related TDP-43 with Sclerosis (CARTS), with: ** TDP-43 pathology, limited to amygdala ** No morphologic hippocampal sclerosis ** Arteriolosclerosis, severe * Primary age-related tauopathy (PART), Braak neurofibrillary stage II-III * Argyrophilic grains (AGs) involving structures of mesial temporal lobe * Vascular brain injury (VBI), acute and remote infarcts, bilateral Comment: A combination of vascular brain injury and age-related neuropathologies are present, including primary age-related tauopathy (PART), argyrophilic grains (AGs), and cerebral age-related TDP-43 with sclerosis (CARTS).
Arteriolosclerosis that affects multiple brain regions is linked to hippocampal sclerosis of ageing.
An association between global parkinsonian score and arteriolosclerosis was no longer statistically significant after accounting for infarcts, the investigators noted.
However, each type of pathology (arteriolosclerosis, microinfarcts, and macroinfarcts--particularly subcortical microinfarcts and macroinfarcts) was found to be independently and significantly associated with gait disturbance.
Large blood pressure variability aggravates arteriolosclerosis and cortical sclerotic changes in the kidney in hypertensive rats.
Kojima C, Takei T, Ogawa T, Nitta K.Serum complement C3 predicts renal arteriolosclerosis in non-diabetic chronic kidney disease.
The cases with mild arteriolosclerosis had 5.56% [+ or -] 2.73% GS (range, 0%-20%) and 7% [+ or -] 6.6% IF/TA (0%-70%).
A statistically significant rise in creatinine level was observed for different degrees of arteriosclerosis and arteriolosclerosis from preoperative to postoperative period with a mean follow-up ranging from 45.6 to 52.8 months.
The pathology of the kidney in this entity shows prominent, diffuse, and nodular mesangial sclerosis; glomerular basement membrane thickening; and arteriosclerosis and arteriolosclerosis
accompanied with hyalinosis.
Standard textbooks of pathology and numerous other resources consistently list 3 lesions under the term arteriosclerosis: (1) atherosclerosis, (2) Monckeberg medial calcific sclerosis, and (3) arteriolosclerosis. (1-3) These lesions generally share 3 features: (1) they result in stiffening of arterial vessels; (2) they cause thickening of the arterial wall; and (3) in the past, they have been considered "degenerative" diseases.
His contemporaries, Gull and Sutton, (9) introduced the term "arterio-capillary fibrosis" to characterize this phenomenon, which would soon thereafter be referred to as arteriolosclerosis.
Benign nephrosclerosis consisted of hyaline arteriolosclerosis
and arteriosclerosis with elastosis.