Louis have found a way to relieve the joint and muscle pain that often accompanies aromatase inhibitors
, allowing women to continue taking these medications.
Sonia Servaja of Hospital del Mar in Barcelona, and colleagues, assessed the association between 25-hydroxy-vitamin D (25[OH]D) concentrations and bone loss at baseline, after 3 months of supplementation, and after 1 year, in patients receiving aromatase inhibitor
therapy for early-stage breast cancer.
In a double-blind, randomised, Phase III study in women receiving aromatase inhibitor
therapy (n=252), denosumab increased lumbar spine BMD at 12 and 24 months versus placebo (P<0.
The aromatase inhibitors
anastrozole, exemestane and letrozole, within their licensed indications, are recommended as options for the adjuvant treatment of early oestrogen-receptor-positive invasive breast cancer in postmenopausal women.
Thousands of women have already beat breast cancer thanks to recent research on aromatase inhibitors
," says Dr.
The introduction of aromatase inhibitors
in the last 2 years has contributed to the risk of osteoporosis in breast cancer patients, Dr.
The National Institute of Clinical Excellence (Nice)is looking at the use of aromatase inhibitors
in the treatment of early disease and researchers said they hoped that it would soon become more widely available in the UK.
Indeed, no one knows how long the benefits of tamoxifen or the aromatase inhibitors
Serono said aromatase inhibitors
had shown promise in early tests as potential first-line agents for treating infertility.
(Targeted Therapy Drug) Major Producer and Their Market Share
13 ( ANI ): Women being treated with breast cancer drugs known as aromatase inhibitors
could ease the joint pain associated with the drugs by engaging in moderate daily exercise, according to a study.
For most of these patients, blocking estrogen activity with aromatase inhibitors
represents an effective treatment.