ASS1

(redirected from argininosuccinate synthase 1)

ASS1

A gene on chromosome 9q34.1 that encodes an enzyme which catalyses the penultimate step of the arginine biosynthetic pathway.
 
Molecular pathology
ASS1 mutations cause citrullinemia type 1.
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References in periodicals archive ?
In addition, similar elevation of transferrin (TF), peroxiredoxin 1 (PRDX1) and 3 (PRDX3), and progesterone receptor membrane component 1 (PGRMC1) and downregulation of urea cycle enzymes such as arginase 1 (ARG1), carbamoyl-phosphate synthase 1 (CPS1), argininosuccinate lyase (ASL), ornithine carbamoyltransferase (OTC), and argininosuccinate synthase 1 (ASS1) in the surrounding liver tissue of both the [Ogg1.sup.-/-] and [Ogg1.sup.+/+] PB groups were found.