Patients with cerebellar ataxia, neuropathy, and vestibular areflexia
syndrome have a very characteristic positive visually enhanced vestibulo-ocular reflex test which indicates concomitant central and peripheral vestibular deficit.
The patient was discharged 8 days later with a diagnosis of acute demyelinating polyneuropathy with sensory predominance and probable Guillain-Barre syndrome due to areflexia
, hyperproteinorrhachia, and the clinical picture of the infection that occurred 3 weeks earlier.
With AIDP, clinical features would include hyporeflexia, areflexia
, or weakness in all limbs, while supportive features would include the following electrophysiological evidence.
Halmagyi et al., "Sensory neuropathy as part of the cerebellar ataxia neuropathy vestibular areflexia
syndrome," Neurology, vol.
On day 16 patient returns to an ER with double vision, mild slurred speech, bilateral facial paralysis, ataxia, areflexia
, and ascending weakness.
Clinical neuromuscular findings include areflexia
, sensory-motor type neuropathy, weakness and muscular atrophy, whereas myopathic findings are rare in muscle biopsy and ENMG (9, 10).
The clinical characteristics associated with "classical" PCH1 are severe hypotonia, areflexia
, muscle weakness, central visual impairment, dysphagia, respiratory insufficiency, and acquired microcephaly with clinical onset in the first months of life and death in early infancy.
Clinical features of neurobrucellosis include back pain, areflexia
, paraparesis, cranial nerve involvement, myelitis, and meningovascular involvement including strokes, neuropathy, or depression.
 found that 13/15 patients (86%) presented vestibular hypofunction or areflexia
; Sugiura et al.
Importantly, only 45.1% had documented brainstem areflexia
and absent motor response .
In addition, signs including apnea, areflexia
, and hypothermia may also be observed.
and electrophysiological evidence of proximal affection was common, reflecting proximal spread of neuropathic process.