the colonic smooth muscle motility via M3 receptor in rabbits," Chinese Journal of Physiology, vol.
is the main alkaloid ingredient in BQ followed by arecaidine.
In a normal tissue, collagen is degraded by phagocytosis whereas in OSMF, arecoline
suppresses T cell activity which in turn decreases the cell mediated immunity resulting in decreased phagocytosis.
, an alkaloid present in betel nut reportedly showed hypoglycemic activities (Chempakam, 1993).
Gomez et al., "The muscarinic cholinergic agonist arecoline
stimulates the rat hypothalamic-pituitary-adrenal axis through a centrally-mediated corticotropin-releasing hormone-dependent mechanism, " Endocrinology, vol.
When chewed, it produces the chemical arecoline
, a mild stimulant, as well as a bright-red juice that stains teeth and footpaths all over Southeast Asia.
We have chosen the brownish white color derived from thin sliced pieces of the nuts which have a high qualitative content of Arecoline
as one of the active ingredients in antihelmintic action of Areca catechu Linn.
It contains three major alkaloids: arecoline
, pilocarpine, and muscarine.
Some studies have proved that arecoline
in areca nut is the main causative agent and tannin which is a protein, can have synergistic role.
Prenatal exposure to arecoline
(areca nut alkaloid) and birth outcomes.
Betel nuts contain the alkaloid arecoline
a mild stimulant that produces a feeling of well being.
It was also found that convolvine potentiates the effects of arecoline
, a muscarinic memory enhancer that ameliorates cognitive deficits in Alzheimer's disease (Asthana 1996, Mirzaev 1998).