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Abbreviation for angiotensin receptor blocker.
Farlex Partner Medical Dictionary © Farlex 2012
angiotensin II receptor blocker
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
angiotensin II receptor antagonistAny of a family of agents (e.g., losartan and valsartan) that block the binding of angiotensin II (A-II) to their cognate cell receptors—AT1, AT2 and others. First-generation ARAs included the sartan family of agents, which only block AT1, interacting with the amino acids in the transmembrane domains to block the binding of A-II to AT1.
ARAs are an alternative to ACEI therapy in patients with CHF; unlike ACEIs, ARAs do not interfere with bradykinin and prostaglandin metabolism, interference of which has been linked to some of the adverse effects of ACEI therapy, particularly to cough and angioedema.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
Abbreviation for angiotensin II receptor blocker.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012