arachidonic acid


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Related to arachidonic acid: arachidonic acid cascade

arachidonic acid

 [ah-rak″ĭ-don´ik]
an essential fatty acid that cannot be synthesized by animal tissues and must be obtained in the diet.

ar·a·chi·don·ic ac·id

(ă-rak-i-don'ik as'id),
An unsaturated fatty acid, usually essential in nutrition; the biologic precursor of the prostaglandins, the thromboxanes, and the leukotrienes (collectively known as eicosanoids).

arachidonic acid

/arach·i·don·ic acid/ (ah-rak″ĭ-don´ik) a polyunsaturated 20-carbon essential fatty acid occurring in animal fats and formed by biosynthesis from linoleic acid; it is a precursor to leukotrienes, prostaglandins, and thromboxane.

arachidonic acid

(ăr′ə-kĭ-dŏn′ĭk)
n.
An unsaturated fatty acid, C20H32O2, present in animal fats and synthesized by the body from linoleic acid, that is essential in human nutrition and is a precursor in the biosynthesis of some prostaglandins.

arachidonic acid

[ar′əkidon′ik]
Etymology: L, arachos, a legume
a long-chain polyunsaturated fatty acid that is a component of lecithin and serves as a starting material in the biosynthesis of prostaglandins and leukotrienes. In mammals, arachidonic acid is synthesized from linoleic acid.

arachidonic acid

Biochemistry
A polyunsaturated omega-6 fatty acid, which is an essential dietary component for mammals and the precursor for biosynthesis of prostaglandins, thromboxanes and hydroxy-eicosatetraenoic acid derivatives (e.g., leukotrienes). Arachidonic acid release from phospholipids is the limiting step in forming its active metabolites.

Nutrition
Foods containing arachidonic acid—e.g., egg yolks, fatty red meat and organ meats—are viewed as unhealthy by nutritionists.

ar·a·chi·don·ic ac·id

(ar'ă-ki-don'ik as'id)
Liquid unsaturated fatty acid that occurs in most animal fats; considered essential in animal nutrition.

arachidonic acid

An unsaturated fatty acid, formed from LINOLENIC acid, and a precursor of prostaglandins and thomboxanes.

arachidonic acid

cell membrane constituent which undergoes degradation during inflammation to form prostaglandins and cytokines, with resultant increase in the inflammatory response; arachidonic acid breakdown is disrupted by non-steroidal anti-inflammatory drugs, aspirin and steroids (see aspirin; non-steroidal anti-inflammatory drugs; steroids)

ar·a·chi·don·ic ac·id

(ar'ă-ki-don'ik as'id)
An unsaturated fatty acid, usually essential in nutrition; the biologic precursor of the prostaglandins, the thromboxanes, and the leukotrienes (collectively known as eicosanoids).

arachidonic acid (ar´əkədon´ik),

n an essential fatty acid that is a com-ponent of lecithin and a basic material for the biosynthesis of some prostaglandins.
Arachnia propionica,
n an opportunistic, naturally occurring organism in the body, especially in body cavities and on the skin. It is sometimes implicated in actinomycosis, especially in open wounds.

arachidonic acid

twenty carbon fatty acid containing four double bonds of the n-6 family essential fatty acids from which prostaglandins, thromboxane and leukotrienes are derived. Deficiency, which is characterized by hair loss, fatty liver degeneration, anemia and reduced fertility, occurs most commonly in cats because of their inability to synthesize arachidonic acid from linoleic acid.
References in periodicals archive ?
Efficacy and safety of arachidonic acid for treatment of Schistosoma mansoni-infected children in Menoufiya, Egypt.
For technical data and manufacturing plants analysis, the report analyzes Arachidonic Acid (ARA) leading suppliers on capacity, commercial production date, manufacturing plants distribution, R&D status, technology sources, and raw materials sources.
erinaceus specifically inhibited collagen-induced platelet aggregation through the inhibition of upstream of arachidonic acid liberation in integrin [alpha]2/[beta]1 signaling.
Of the included subjects, two had baseline whole-blood impedance platelet aggregation of less than 8[ohms] utilizing the 5[micro]M concentration of ADP; one of these two also had < 8[ohms] with collagen and arachidonic acid agonists.
In an earlier phase of the study, he said, arachidonic acid failed to show the expected aspirin inhibition in 17 of 192 heart attack patients who had been prescribed aspirin.
The relationships of total plasma PUFAs, n-3 FA, linolenic acid, n-6 FA, linoleic acid, and arachidonic acid with change in creatinine clearance from baseline to follow-up was examined using multivariate linear regression models adjusted for covariates, including education, cigarette smoking (pack-years), MMSE score, energy intake, alcohol intake, LDL cholesterol, HDL cholesterol, cancer, cardiovascular disease, and hypertension (Table 2).
Currently aspirin therapy is monitored using platelet aggregation to measure the dose-response curve to diverse platelet activators including adrenaline, ADP, arachidonic acid and collagen.
Although the molecular mechanisms that attenuate the extent of LPS-induced production of lipid mediators are not well discerned, a growing body of evidence suggests that the initial event in the generation of proinflammatory lipids is the liberation of arachidonic acid from membrane phospholipids by activation of cytosolic phospholipase [A.
Rather, the level of arachidonic acid is lower in the elderly male than the young female.
Role of arachidonic acid metabolism in the mitogenic response of Balb/c 3t3 fibroblasts to epidermal growth factor.