arachidonic acid


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Related to arachidonic acid: arachidonic acid cascade

arachidonic acid

 [ah-rak″ĭ-don´ik]
an essential fatty acid that cannot be synthesized by animal tissues and must be obtained in the diet.

ar·a·chi·don·ic ac·id

(ă-rak-i-don'ik as'id),
An unsaturated fatty acid, usually essential in nutrition; the biologic precursor of the prostaglandins, the thromboxanes, and the leukotrienes (collectively known as eicosanoids).

arachidonic acid

(ăr′ə-kĭ-dŏn′ĭk)
n.
An unsaturated fatty acid, C20H32O2, present in animal fats and synthesized by the body from linoleic acid, that is essential in human nutrition and is a precursor in the biosynthesis of some prostaglandins.

arachidonic acid

Biochemistry
A polyunsaturated omega-6 fatty acid, which is an essential dietary component for mammals and the precursor for biosynthesis of prostaglandins, thromboxanes and hydroxy-eicosatetraenoic acid derivatives (e.g., leukotrienes). Arachidonic acid release from phospholipids is the limiting step in forming its active metabolites.

Nutrition
Foods containing arachidonic acid—e.g., egg yolks, fatty red meat and organ meats—are viewed as unhealthy by nutritionists.

ar·a·chi·don·ic ac·id

(ar'ă-ki-don'ik as'id)
Liquid unsaturated fatty acid that occurs in most animal fats; considered essential in animal nutrition.

arachidonic acid

An unsaturated fatty acid, formed from LINOLENIC acid, and a precursor of prostaglandins and thomboxanes.

ar·a·chi·don·ic ac·id

(ar'ă-ki-don'ik as'id)
An unsaturated fatty acid, usually essential in nutrition; the biologic precursor of the prostaglandins, the thromboxanes, and the leukotrienes (collectively known as eicosanoids).
References in periodicals archive ?
Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels.
(2007) inhibited simultaneously COX-2 and 5-LOX pathways of arachidonic acid in human lung cancer cells with drug combinations and concluded that COX and LOX together are more potent in suppression of proliferation and stimulation of cell death.
HEK293 cells that expressed the necessary machinery to convert arachidonic acid into LTs [25, 41] were stimulated in the presence of exogenous arachidonic acid, thus bypassing a critical step in the bioavailability of the 5LO substrate.
Free activated arachidonic acid not bound to COX-2 may be also used by 5-LOX to produce leukotrienes during inflammation in vivo [42].
Ward, "Production of arachidonic acid by Mortierella alpina ATCC 32222," Journal of Industrial Microbiology, vol.
Our data showed that shokyo did not suppress COX-2 expression and that shokyo did not alter [PGE.sub.2] production when arachidonic acid or [PGH.sub.2] is added to bypass their upstream pathway.
In our study the arachidonic acid a beneficent fatty acid as discussed earlier was the dominant among all -6 fatty acid.
The primary endpoint was PAR induced by arachidonic acid at discharge, and the secondary endpoint was the rate of thrombotic events including brain infarction and myocardial infarction during follow-up.
Arachidonic acid was topically applied to induce irritation and swelling, which led to oedema.
4-Hydroxy-2-nonenal (HNE) is known to be the main aldehyde formed during lipid peroxidation of n-6 polyunsaturated fatty acids, such as linoleic acid C18:2 n-6 and arachidonic acid C20:4 n-6.
Arachidonic acid, one of PUFA acids, is a major substrate for the 12/15-LOX.
Matsumata et al., "Arachidonic acid drives postnatal neurogenesis and elicits a beneficial effect on prepulse inhibition, a biological trait of psychiatric illnesses" PLoS ONE, vol.