apudoma


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apudoma

 [ah″pu-do´mah]
a tumor derived from APUD cells, many of which secrete ectopic hormones.

APUDoma

A tumour that produces small peptide hormones of the APUD system
Examples Small (oat) cell carcinoma of lung, medullary carcinoma of thyroid, pancreatic islet cell tumour, ganglioneuroma, and carcinoids of lung, thymus, GI tract, and prostate.
Clinical findings Heterogeneous; reflects functional nature of tumour and/or metastases.
Note on terminology: APUDoma is little used in the working parlance and been replaced by “neuroendocrine tumour”.

APUDoma

Oncology A tumor that produces small peptide hormones of the APUD system Examples Small–oat cell carcinoma of lung, carcinoids of lung, thymus, GI tract and prostate, medullary CA of thyroid, pancreatic islet cell tumor, malignant melanoma, ganglioneuroma Clinical Heterogeneous; reflects functional nature of tumor and/or metastases. See MEN.
References in periodicals archive ?
Malignant apudoma of the liver with symptomatic intractable hypoglycemia.
El hallazgo de niveles alterados de cortisol (am 406.6 ng/mL, pm 327.8 ng/mL) y acido vanilmandelico en orina (21.4 mg/24h) lleva a las sospechas diagnosticas de sindrome de Cushing, apudoma de localizacion indeterminada y feocromocitoma; sin embargo, estudios complementarios (test de supresion con dexametasona, RMN de glandulas adrenales, RMN de silla turca, TAC de torax simple y contrastado) descartaron dichos diagnosticos.
Polidoro, "Simultaneous primary oat cell carcinoma (Apudoma) and squamous cell carcinoma of the hypopharynx," ORL, vol.
Durante los ultimos anos ha recibido diversas denominaciones: tumor neuroepitelial cutaneo primario, carcinoma de celulas pequenas cutaneo primario, carcinoide cutaneo primario, APUDoma cutaneo y neuroblastoma del adulto [6].
SPD'de otoimmun mekanizmalar sorgulanmis ve piyoderma gangrenozum, romatoid artrit, sistemik lupus eritematozus, enfiamatuar barsak hastaliklan, hipertiroidizm, multipl miyelom, benin monoklonal IgA, IgG ve IgM gammopatileri ve apudoma ile birliktelikler bildirilmistir (12).