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a tumor derived from APUD cells, many of which secrete ectopic hormones.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
APUDomaA tumour that produces small peptide hormones of the APUD system
Examples Small (oat) cell carcinoma of lung, medullary carcinoma of thyroid, pancreatic islet cell tumour, ganglioneuroma, and carcinoids of lung, thymus, GI tract, and prostate.
Clinical findings Heterogeneous; reflects functional nature of tumour and/or metastases.
Note on terminology: APUDoma is little used in the working parlance and been replaced by “neuroendocrine tumour”.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
APUDomaOncology A tumor that produces small peptide hormones of the APUD system Examples Small–oat cell carcinoma of lung, carcinoids of lung, thymus, GI tract and prostate, medullary CA of thyroid, pancreatic islet cell tumor, malignant melanoma, ganglioneuroma Clinical Heterogeneous; reflects functional nature of tumor and/or metastases. See MEN.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.