apoptotic cell

apoptotic cell

Cell biology A dense, eosinophilic, pyknotic cell surrounded by a thin clear space, often lying within epithelium, which is due to apoptosis
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MEASUREMENT OF APOPTOTIC CELL ISOLATION EFFICIENCY WITH TRIFUNCTIONAL AVIDIN-COUPLED NANOSPHERES
trachomatis and mammalian host cells have been made but the effects of LPS on apoptotic cell death differ among cell types and cell lines and to the best of our knowledge the apoptotic effect of C.
In animal models, histologic findings resemble apoptotic cell death rather than necrosis.
Aegera is a private North American biotechnology company focused on exploiting apoptosis control to extend and enhance the lives of cancer patients: killing cancer cells by inducing apoptosis and rescuing nerve cells from apoptotic cell death caused by chemotherapy.
Biochemical data are consistent with the hypothesis that CV1013 inhibited primarily caspase 8, thereby blocking the initial intracellular signal that would be expected to lead to apoptotic cell death and liver failure.
Often, neighboring cells eat the apoptotic cell fragments, so the latter disappear completely within an hour after apoptosis activation.
Although the observation of necrotic cells in such situations complicates the issue, and indeed, is a subject beyond the scope of this article, it is now becoming generally accepted that apoptotic cell death is an early and important event in ischemia/reperfusion-related tissue and organ damage.
Birinapant (formerly TL32711) is a small molecule peptidomimetic of Smac (Second mitochondrial-derived activator of caspases), an endogenous regulator of apoptotic cell death that selectively antagonizes multiple Inhibitor of Apoptosis Proteins (IAPs).
Treatments with 150, 200 and 250 uM licofelone caused early apoptotic cell rates of 4, 15 and 24 % for 24 h and 6, 13 and 24 % for 48 h, respectively.
There was no apoptotic cell in the epidermis of the control group.
Morphological observation of DAPI and Acridine Orange/Propodium Iodide staining was documented by typical characteristics of apoptotic cell death.
On the other hand, clearance of apoptotic cell prevents release of toxic contents from dying cells, promotes resolution of inflammation and produces growth factors that enhances macrophases clearance of apoptotic cells.

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