apoptotic cell

apoptotic cell

Cell biology A dense, eosinophilic, pyknotic cell surrounded by a thin clear space, often lying within epithelium, which is due to apoptosis
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It decreased phosphorylation of signal transducer and activator of transcription (STAT3/5) proteins, inhibited cell proliferation and induced apoptotic cell death in cell models expressing mutationally active JAK2 or FLT3.
US FDA approves Celgene's Inrebic
Apoptotic cell death has been demonstrated as the main mechanism of germ-cell loss in the perinatal period.
Apoptosis, Autophagy, and Necrosis in Murine Embryonic Gonadal Ridges and Neonatal Ovaries: An Animal Model
In one model; the main role of the P53 pathway in determining cell destiny has been suggested either to activate the control points in the cell cycle or facilitate repair, thereby increasing survival or, inducing apoptotic cell death (28-30).
The Antiproliferative Activity of Colchicum umbrosum Plant Extract and Paclitaxel on C-41 and Vero Cells
Apoptotic cell death was determined using annexin-V-fluorescein isothiocyanate (FITC)/7-amino-actinomycin D (7-AAD; BD Biosciences) and Cycletest[TM] Plus DNA Reagent Kit (BD Biosciences) in all cells.
Comparison of Cisplatin with Lipoplatin in Terms of Ototoxicity
"Metformin also induced endoplasmic reticulum stress and subsequent apoptotic cell death via the activation the proapoptotic family members," she said.
QU-CHS graduate unveils neoadjuvant drug for treatment of breast cancer
Mouse primary ESCs of different passages (passage 4 or 19) were employed and cell proliferation, mitochondrial ATP production, reactive oxygen species (ROS) generation, and apoptotic cell numbers of the ESCs were monitored after being post-thaw subcultured different times.
The importance of post-thaw subculture for standardizing cellular activity of fresh or cryopreserved mouse embryonic stem cells
They exhibit decreased apoptotic cell death, compared with normal skin.
High-dose hydrogen peroxide for SKs
Having tools to study DNA damage and the apoptotic cell process is an important aspect of understanding drug action.
Bio-Techne Acquires US Biotechnology Firm Trevigen in Cash Transaction
Caspases are proteases which play critical role in the initiation and execution of apoptotic cell death.14
Metformin attenuate PTZ-induced apoptotic neurodegeneration in human cortical neuronal cells
Approaches in activating NRF2, such as administration of the NRF2 activator sulforaphane (SFN) [5, 6], supplementation of zinc [15], and exposure to low-dose X-irradiation [8], effectively ameliorated diabetes-induced testicular inflammation, ER stress, and apoptotic cell death, in rodent models of both type 1 and type 2 diabetes.
NRF2 Plays a Critical Role in Both Self and EGCG Protection against Diabetic Testicular Damage
In conclusion, our results showed that the Spatholobus suberectus column extract (SSCE) induced apoptotic cell cycle arrest of MCF-7 cells, inhibited activity of nucleus p-ER[alpha] and p-ER[beta], and downregulated the expression of p-ER[alpha], which resulted in suppression of the MAPK PI3K/AKT pathway.
Spatholobus suberectus Column Extract Inhibits Estrogen Receptor Positive Breast Cancer via Suppressing ER MAPK PI3K/AKT Pathway
Oh et al., "Inhibition of inflammation and oxidative stress by Angelica dahuricae radix extract decreases apoptotic cell death and improves functional recovery after spinal cord injury," Journal of Neuroscience Research, vol.
The Neuroprotective Effects of Muscle-Derived Stem Cells via Brain-Derived Neurotrophic Factor in Spinal Cord Injury Model

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