apoprotein


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Related to apoprotein: Holoprotein

apoprotein

 [ap″o-pro´tēn]
the protein portion of a molecule or complex consisting of a protein molecule joined to a nonprotein protein molecule or molecules (such as a lipoprotein).

ap·o·pro·tein

(ap'ō-prō'tēn),
A polypeptide chain (protein) that has not yet formed a complex with the prosthetic group required to form the active holoprotein.

apoprotein

The protein part of a biomolecular complex without its ligand or prothetic group (e.g., ferritin without ferric hydroxide = apoferritin).

ap·o·pro·tein

(ap'ō-prō'tēn)
A polypeptide chain (protein) not yet complexed with the prosthetic group that is necessary to form the active holoprotein.
References in periodicals archive ?
This may be due to a change in the properties of the apoprotein, changes in the conformation of the chromophore, and/or changes in the interaction between the apoprotein and the chromophore.
The concentration of chlorophyll-a in algal cells declines under nitrogen limitation, because nitrogen is a major constituent of this pigment and its apoprotein (Heraud et al., 2007).
The ensuing chapters discuss apolipoprotein A-1 mutations, diversity of high-density lipoproteins, reverse cholesterol transport, ATP-binding cassette transporter A1 and G1, sphingolipids, lecithin and cholesterol acyltransferase, cholesteryl ester transfer protein inhibitors, apoprotein mimetic peptides, oxidized HDL, paraoxonase-1, and use of proteomics techniques in HDL research.
HDL and DiI-HDL showed no differences in apoprotein composition on 12% SDS-PAGE [44].
For example Kynamro, an antisense inhibitor of apolipoprotein B [32], the principal apoprotein present on all atherogenic lipids [38], was approved by the FDA in January 2013 for use as an adjunct to first-line lipid-lowering therapies in homozygous familial hypercholesterolemia [39-41].
As a result of these findings, it is expressed that SAA was the main apoprotein in HDL during the onset of sepsis.
(9) showed a paradoxical decrease in the high-density lipoprotein fraction of cholesterol and in apolipoprotein AI, and an increase in the apoprotein B/apoprotein AI ratio in the sportsmen, compared with the reference group.
(8) Within the intima lining, apoprotein B-100 has the potential to become oxidized.
By day 4 to 5 after MI there is a significant decrease in the serum concentration of apoprotein A-I and apoprotein B, reflecting the maximum decrease in serum TC, HDL, and LDL3.
Longer (5 month) exposures exacerbated the progression of atherosclerosis in hyperlipidemic, apoprotein E-deficient (Apo[E.sup.[-/-]]) mice.