The differential diagnoses6 that should be considered with CFPTs are desmoid tumours, solitary fibrous tumour, desmoplastic fibroblastoma, calcifying
aponeurotic fibroma, collagenous fibroma and other sub categories of inflammatory pseudotumours (focal myositis, plasma cell granuloma, inflammatory myofibroblastic tumour etc).6 The diagnosis of CFPT requires clinical exclusion of neoplasms and absence of active infectious processes.
It differs from other fibrous conditions such as fibromatosis, juvenile
aponeurotic fibroma, subepidermal nodular fibrosis, and dermatofibrosarcoma protuberans.
FNAC of calcifying
aponeurotic fibroma, collagenous fibroma, and fibroma of tendon sheath showed spindle cells lying dispersed and in packed clusters against clean background, showing predominantly a spindle cell pattern.
There has been a case reported of intratendinous aponeurotic fibroma within the substance of the flexor pollicus longus by Moskovich.
(2.) Moskovich R, Intratendinous aponeurotic fibroma: J Hand Surg 1988 July: 13 (4):563-566
The principal clinical differential diagnosis are extraskeletal mesenchimal chondrosarcoma, giant cell tumor of the tendon sheath with foci of cartilaginous metaplasia, calcifying
aponeurotic fibroma, synovial chondromatosis, and nodular chondrometaplasia.
(4,5) Associations with this tumor have been reported in the past, such as hemangiomas and juvenile
aponeurotic fibromas. (6)