apolipoprotein C-II

ap·o·lip·o·pro·tein C-II

an apolipoprotein found in VLDL, HDL, and chylomicrons; an activator of lipoprotein lipase; a deficiency will result in accumulation of chylomicrons and triacylglycerols.


A gene on chromosome 19q13.2 that encodes apolipoprotein C-II, a member of the apolipoprotein C family which is expressed primarily in the liver and activated when monocytes differentiate into macrophages.
References in periodicals archive ?
Using 2D electrophoresis and mass spectrometry, a pattern of 11 circulating protein markers including apolipoprotein C-II, apolipoprotein B, transthyretin, and C3 showed some capacity to segregate BA patients.
Major peaks are observed corresponding to IgG, albumin dimer, transferrin, albumin, doubly charged albumin, apolipoprotein A-I, transthyretin, apolipoprotein C-III, apolipoprotein C-II, and apolipoprotein C-I.
Hypertriglyceridemia associated with deficiency of apolipoprotein C-II. N Engl J Med 1978; 298:1265-73.