Using 2D electrophoresis and mass spectrometry, a pattern of 11 circulating protein markers including apolipoprotein C-II
, apolipoprotein B, transthyretin, and C3 showed some capacity to segregate BA patients.
Major peaks are observed corresponding to IgG, albumin dimer, transferrin, albumin, doubly charged albumin, apolipoprotein A-I, transthyretin, apolipoprotein C-III, apolipoprotein C-II
, and apolipoprotein C-I.
Hypertriglyceridemia associated with deficiency of apolipoprotein C-II
. N Engl J Med 1978; 298:1265-73.