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an apolipoprotein found in VLDL and chylomicrons. It modulates the interaction of apolipoprotein E with VLDL.
Farlex Partner Medical Dictionary © Farlex 2012
APOC1A gene on chromosome 19q13.2 that encodes a member of the apolipoprotein C1 family expressed primarily in the liver and activated when monocytes differentiate into macrophages. APOC1 is thought to modulate the interaction of APOE with beta-migrating VLDL and inhibit beta-VLDL binding to the LDL-receptor-related protein. It binds free fatty acids and reduces their intracellular esterification.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.