apolipoprotein B100

apolipoprotein B100

A protein encoded by APOB on chromosome 2p24-p23, a major chylomicron component synthesised in the intestine that is essential for intestinal absorption of dietary fats and fat-soluble vitamins.
References in periodicals archive ?
The large global INTERHEART study in 52 countries indicated that smoking, exercise, fruit and vegetable intake, alcohol, hypertension, diabetes, abdominal obesity, psychosocial factors, and high apolipoprotein B100 (ApoB)/apolipoprotein A1 (ApoA1) ratio were associated with AMI.[6],[7] In addition to ApoB/ApoA1, Karthikeyan et al .[3] investigated the role of other lipid indexes of AMI risk in the Asian population.
In this specific case, a single haplotype, X+Del may contribute to structural changes that occur in apolipoprotein B100 caused by this variation, compromising the interaction between apolipoproteins and LDL receptors, leading to the accumulation of LDL in circulation (9,10,27,28).
Shepherd, "Influence of apolipoprotein E polymorphism on apolipoprotein B100 metabolism in normolipemic subjects," Journal of Clinical Investigation, vol.
Serum apolipoprotein A1 (APO-A1), apolipoprotein B100 (APO-B100) and lipoprotein-(a) (LPA) were measured in the Pathology Laboratories of Postgraduate Lady Reading Hospital, Peshawar using turbiditrimetric kits of Roche Diagnostics, on chemistry auto analyzer, modular P-800 by Roche, Cobas (Japan).
Study conducted to investigate the biochemical changes in the blood (apolipoprotein B100 and some lipid components) of crossbred cows (Brown Swiss x Baladi) during the transition period under hot and thermoneutral environments.
Apolipoprotein B100 (Apo B) molecule is present in all major atherogenic particles (VLDL, IDL, LDL).
(12) Furthermore, the VAP test provides measurements of various lipid components including HDL, TC (VLDL), non-HDL, apolipoprotein B100 (apoB100), Lp(a), IDL, LDL-R, LDL-R subclasses, and remnant lipoproteins such as VLDL3.
The selective retention of circulating apolipoprotein B100 containing lipoproteins in the subendothelial space, by means of specific interactions with artery wall proteoglycans, is currently thought to be the leading event in atherogenesis [3, 4].
At the end of 12 weeks, total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), very-low-density lipoprotein cholesterol (VLDL-C), and apolipoprotein B100 (Apo B100) were significantly lower in the soy nut group compared with the control group.
Apolipoprotein B100 metabolism in autosomal-dominant hypercholesterolemia related to mutations in PCSK9.
Innerarity, "The molecular mechanism for the genetic disorder familial defective apolipoprotein B100," Journal of Biological Chemistry, vol.
Association of high-density lipoprotein cholesterol with incident cardiovascular events in women, by low-density lipoprotein cholesterol and apolipoprotein B100 Levels: a cohort study.