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an apolipoprotein found in LDL, VLDL, and IDL. The ligand for the LDL receptor; absent in certain types of abetalipoproteinemia.
Farlex Partner Medical Dictionary © Farlex 2012
APOBA gene on chromosome 2p24-p23 that encodes apolipoprotein B, the main apoliprotein of chylomicrons and low-density lipoproteins, which appears in plasma as two main isoforms: apoB48 (which is synthesised exclusively in the gut) and apoB100 (which is synthesised in the liver).
APOB mutations cause hypobetalipoproteinaemia, normotriglyceridemic hypobetalipoproteinaemia, and hypercholesterolaemia due to ligand-defective apoB.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
apolipoprotein B-100A 550 kD protein synthesized in the liver that is the major component in lipoproteins of endogenous origin–LDL, VLDL, IDL, provides the recognition signal targeting LDL to the LDL–apoB, E receptor and is considered to be the l'enfant terrible of ASHD Ref range 40 to 125 mg/dl Abnormal values ↑ in familial combined hyperlipidemia, acquired hyperlipidemia, in acute angina and MI
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.