apolipoprotein A-IV

ap·o·lip·o·pro·tein A-IV

an apolipoprotein secreted with chylomicrons and also found in HDL. It participates in the catabolism of chylomicrons and VLDL. It is also required for activation of lipoprotein lipase and LCAT.

APOA4

A gene on chromosome 11q23 that encodes apolipoprotein A-IV, which is a major component of high-density lipoprotein (HDL) and chylomicrons. It plays a role in chylomicrons and VLDL secretion and catabolism, and is required for efficient activation of lipoprotein lipase by ApoC-II. It is a potent activator of lecithin-cholesterol acyltransferase (LCAT).
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The eight differentially expressed proteins included third party data (TPA): vitamin D-binding protein precursor (GC), complement C4 precursor (C4), paraoxonase 1 (PONI), A2M, endopin 1 (EN1), TPA: apolipoprotein A-IV precursor (APOA4), alpha-1-antitrypsin, and haptoglobin (HP).
Kohan AB, Wang F, Li X, et al Apolipoprotein A-IV regulates chylomicron metabolism-mechanism and function.
Differentially expressed serum proteins associated with calcium regulation and hypocalcemia in dairy cows
Patrick Tso, PhD, professor in the UC Department of Pathology and Laboratory Medicine, has revealed that apolipoprotein A-IV (apoA-IV) is secreted by the small intestine in response to fat absorption.
Target for diabetes drug identified
Increased apolipoprotein A-IV in rat mesenteric lymph after lipid meal acts as a physiological signal for satiation.
The -256T>C polymorphism in the apolipoprotein A-II gene promoter is associated with body mass index and food intake in the genetics of lipid lowering drugs and diet network study
Identified proteins with expression that decreased with As exposure (higher intensity in the control gel or absent in the As-treated gel) were RAGE, glutathione-S-transferase (GST)-omega-1, contraspin (a serine--or cysteine--proteinase inhibitor isoform), apolipoprotein A-IV, and apolipoprotein A-I.
Pulmonary biomarkers based on alterations in protein expression after exposure to arsenic
The biological role of apolipoprotein A-IV on chromosome segregation needs to be further investigated.
Asociacion entre la perdida del cromosoma x en mujeres de edad avanzada y el polimorfismo de la apolipoproteina A-IV:360 GLN/HIS
PNAS report suggests Apolipoprotein A-IV plays important role in regulating glucose homeostasis
Apofore Founder Publishes Studies Identifying Apolipoprotein A-IV as New Potential Target for Type 2 Diabetes Therapeutics
1]B-Glycoprotein 3-6 23 Apolipoprotein A-IV 3-6 24 Apolipoprotein C-II 2-7 25 [[beta].
The MALDI-TOF mass spectrometric view of the plasma proteome and peptidome
Genes involved in fatty acid synthesis, such as acetyl-CoA-carboxylase and elongation of long-chain fatty acids were reduced only by PCB-77 in corn-oil--fed mice, whereas lipid transport/export genes such as fatty acid binding protein 2 and 4, ATP-binding cassette A1, and apolipoprotein A-IV were altered in olive-oil--fed mice in response to PCBs.
Dietary fat interacts with PCBs to induce changes in lipid metabolism in mice deficient in low-density lipoprotein receptor
Apolipoprotein A-IV (apo A-IV) is a 46-kDa plasma protein (1) with different isoforms (2).
Apolipoprotein A-IV in the fed and fasting states
Human Apolipoprotein A-IV binds to apolipoprotein A-I/A-II receptor sites and promotes cholesterol efflux from adipose cells.
Quantitative measurement of lipoprotein particles containing both apolipoprotein AIV and apolipoprotein B in human plasma by a noncompetitive ELISA
A novel polymorphism of apolipoprotein A-IV is the result of an asparagine to serine substitution at residue 127.
Association between genetic variations of apo AI-CIII-AIV cluster gene and hypertriglyceridemic subjects

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