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1. a carcinoma composed predominantly of cells with abundant eosinophilic granular cytoplasm, occurring in the breast or other sites;
2. a carcinoma of the apocrine glands.
apocrine carcinomaAn uncommon type of breast carcinoma (±4% of all breast cancers) for which 90+% of the malignant cells are defined as apocrine, either by immunohistochemistry (GCDFP-15, androgen receptor +ve) or cytologically (eosinophilic cells with prominent nucleoli).
ap·o·crine car·ci·no·ma(ap'ō-krin kahr'si-nō'mă)
1. A carcinoma composed predominantly of secretory cells with abundant eosinophilic granular cytoplasm, occurring in the breast.
2. A carcinoma of the apocrine glands, especially those found in the groin and axilla.