aplastic anaemia


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Related to aplastic anaemia: megaloblastic anaemia

aplastic anaemia

Anaemia due to a failure in marrow production of RBCs, often accompanied by failure in WBC and platelet production (i.e., granulocytopaenia, thrombocytopaenia).
 
Aetiology
Toxins (benzene, toluene, insecticides), radiotherapy, drugs (carbamazepine, chemotherapy, chloramphenicol, gold salts, phenytoin, phenylbutazone, quinacrine, sulfonamides, tolbutamide), autoimmunity, SLE, post-hepatitis, pregnancy, paroxysmal nocturnal haemoglobinuria.

Prognosis
Aplastic anaemia is often unresponsive to specific therapy.

aplastic anaemia

A serious form of anaemia in which no new blood cells are formed in the bone marrow. About 30% of cases follow virus infections, especially MEASLES, MUMPS and HEPATITIS or are induced by drugs such as BUTAZOLIDINE, SULPHONAMIDES, CHLORAMPHENICOL or dipyrone. The condition results from damage to the haemopoietic stem cells often from an autoimmune process that can be checked by immunosuppressive drug treatment. Blood transfusions are often necessary to maintain life.
References in periodicals archive ?
Histopathological analysis of bone marrow trephine biopsy of 40 cases of pancytopenia revealed megaloblastic anaemia as the most common cause of pancytopenia (30%), followed by aplastic anaemia (25%) and hypersplenism (15%).
ALL was the commonest cause of haematological thrombocytopenia followed by ITP and Aplastic anaemia, but low platelet count may occur in many other haematological conditions as well.
Epidemiological features of aplastic anaemia in Pakistan.
Angelo Farrugia, 28, has severe aplastic anaemia and is seeking a third transplant Peter Bolter 250315ANGELO_04
I am trying to raise money for this six years old child, who has Aplastic Anaemia.
But it wasn't until Liam was transferred to the Royal Victoria Infirmary in Newcastle that further tests confirmed aplastic anaemia.
APLASTIC anaemia is a rare blood disorder in which the body's bone marrow doesn't make enough new blood cells.
Eighteen-month-old Beth Heaton was diagnosed with aplastic anaemia at the age four months and depended on transfusions until a suitable bone marrow donor could be found.
In the process, they hope to raise PS10,000 for Marsden Scout Group, the Marsden Mechanics Hall and for St James' Hospital's aplastic anaemia unit, which treats their sister, Catherine.
Commonest causes of pancytopenia found were megaloblastic anaemia and aplastic anaemia in 18 (25.
The product is intended for the treatment of hypoplastic myelodysplastic syndrome and aplastic anaemia.
Diagnosis in patients with severe pancytopenia suspected of having aplastic anaemia.