Lozada-Nur, "The diagnosis and management of recurrent aphthous
stomatitis: a consensus approach," Journal of the American Dental Association, vol.
Conclusions: Patients with recurrent aphthous
ulcers had more hematinic deficiencies, particularly of vitamin B12 as compared to controls.
To summarize: persistent and recurring aphthous
ulcers; chronic, persistent, and frequent diarrhea; abdominal pain (likely masked by use of ibuprofen); weight loss (especially crossing of growth channels); decreased appetite; positive hemocult test; elevated inflammatory markers (ESR, platelets, CRP); decreased serum albumin (decreased protein); low Hct and Hgb; and a low MCV (indicating chronic blood loss); Jewish ancestry; and a positive family history.
Colchicine prophylaxis for frequent periodic fever, aphthous
stomatitis, pharyngitis and adenitis episodes.
John Zone, a dermatologist from the University of Utah, Salt Lake City, said at the meeting that about 5% of people with unexplained aphthous
ulcers have occult celiac disease.
While OHCWs do not prescribe these agents, they should be aware of the associated oral complications such as oral aphthous
ulcers or treatment modifications related to use of pharmacological agents in oral care services.
ATHE most common type are aphthous
ulcers which form painful sores on the inside of the cheeks, lips or underneath the tongue.
Ongoing trials continue in the area of HIV/AIDS include AIDS-related cachexia and aphthous
Thalidomide has previously proven effective in the treatment of oral aphthous
ulcers in HIV-infected people.
The infamous drug also appears useful in treating aphthous
ulcers, which form in the mouth and esophagus of some AIDS patients.
Canker sores (also called aphthous
ulcers) are small, shallow ulcers occurring on the tongue, soft palate, or inside the lips and cheeks.
If the blisters are inside your mouth, they could be aphthous
ulcers (a term used to describe painful oral ulcers of unknown cause).