One report demonstrates healing and apexogenesis
following vital pulp therapy for immature permanent teeth diagnosed with reversible and irreversible pulpitis, but this response can be variable (7).
Calcium silicate cements are bioactive materials used in various endodontic indications, such as pulp capping, pulpotomy, apexogenesis
, apexification, perforation repair, and root-end filling [1-4].
Taschieri, "Apexification, apexogenesis
and regenerative endodontic procedures: a review of the literature," Minerva Stomatologica, vol.
A recent systematic review reported that 97 of 101 teeth (96%) treated with REPs between 2001 and 2014 were successfully treated as measured by some degree of apexogenesis
including increased root length, increased root thickness and apical closure.
This technique induces apexogenesis
. It is new treatment modality that uses, instead of tissue replacement using artificial substitutes, tissue regeneration [1, 15].
It has since then been indicated for other uses such as pulp capping, apexogenesis
, and apexification in immature teeth with necrotic pulp, filling of root canals, treatment of horizontal root fractures, internal and external resorption, and repair of perforations .
is done is in immature teeth when part of the pulp tissue inside the root canal remains vital and apparently healthy.
In some cases, apexogenesis
or pulpectomy has been provided either electively or following exposure with a successful outcome [Ignelzi et al.,1990; O'Neal et al., 1997].