However, as we will explain in more detail in the subsequent sections, this cannot be the case as both the MyD88-dependent and the MyD88-independent pathways culminate in the activation and nuclear translocation of transcription factors, and this step would not be applicable in anucleated cells like platelets [2, 12, 26].
Some studies evidenced that the chicken blood contains nucleated blood cells, while mammalian blood contains anucleated cells, which may influence fecundity if nucleated cells contain more nutrition [20, 25].
The function of the anucleated apyrene sperm is still not clear, and although it is not involved in fertilization, it constitutes 50-90% of the total amount of the transferred sperm (Silberglied et al.
These anucleated cells are embedded in a lipid matrix of ceramides, cholesterol, and free fatty acids to form the "brick and mortar" structure of the SC that seals the epidermis and provides protection to the skin (Menon et al.
Once the cells have reached this outer most layer they have gone through a process of differentiation, which has transformed them into dead, flattened, anucleated cells called "coenocytes", which can take between 28 46 days to complete.