antiviral agent


Also found in: Dictionary, Thesaurus, Encyclopedia.
Related to antiviral agent: Antiviral drugs

antiviral agent

Antiviral Infectious disease An agent that prevents viral invasion or replication, treats an infection, or thrashes the virus into latency; antivirals may be specific–see below or nonspecific–eg, IFNs, which stimulate host defenses against viruses, making cells more resistant to viral genes, enhancing cellular immune responses or suppressing viral replication Types Inhibitors of viral DNA replication, transcription, or translation; topical surfactants; those that reduce viral infectivity by altering the lipid envelope; photodynamic inactivation with dyes which, when activated with UV light, are incorporated into the viral DNA, causing reading errors, IFN and IFN inducers, immune modulators and vaccines; AAs should not be used prophylactically, as their use selects for drug-resistant strains of virus.

antiviral agent

an agent that inhibits the REPLICATION of VIRUSES. Very few of these agents are suitable for clinical use, however, mainly because of toxic side effects and/or the occurrence of resistant strains.
References in periodicals archive ?
Nishikawa et al., "Tenofovir and entecavir are the most effective antiviral agents for chronic hepatitis B: a systematic review and Bayesian meta-analyses," Gastroenterology, vol.
The proportion of circulating influenza viruses resistant to oseltamivir increased from 12% during the 2007-08 season to 99% during the 2008-09 season in the United States, and new interim guidelines for use of antiviral agents were released in December 2008 (15).
Further investigations are thus required to understand more of the molecular interactions between SP-2a and the viral particles before SP-2a can be further developed as a novel antiviral agent, especially against ACV-resistant viruses.
Ghany told clinicians that, with the current Food and Drug Administration--approved regimens, "efficacy of therapy is improving and cure is now possible." The addition of direct-acting antiviral agents to regimens previously containing only peginterferon and ribavirin has been "a game-changer," Dr.
Recently, investigators showed that giving a neuraminidase inhibitor to mice infected with influenza virus A (H5N1) was not nearly as effective as treating the mice with an antiviral agent and 2 immunomodulatory agents, mesalazine, a PPAR[gamma] agonist, and celecoxib, a cyclooxygenase (COX)-2 inhibitor (28,29).
She was not identified as having an immunological disorder, and her colitis responded to treatment with ganciclovir, a new antiviral agent.
Teslexivir is a topical antiviral agent that is a potent and selective inhibitor of the interaction between two essential viral proteins, E1 and E2, an interaction that is a necessary step for human papilloma virus DNA replication and thus viral production.
Approved by the FDA in December of 2014, peramivir (Rapivab) is the only antiviral agent for influenza treatment to come to market in nearly 20 years.
The results suggest that a simple chemical change can convert APOBEC3F to a more effective antiviral agent and that shielding of a common feature shared by related proteins may yield a similar outcome, say researchers at the University of Minnesota.
Studies done in the 1980s and 1990s showed that the antiviral agent acylovir reduced levels of Epstein-Barr virus (EBV) in patients with infectious mononucleosis, but did not produce significant clinical benefit.
Tea contains tannin, which is an antibacterial and antiviral agent and protects against dental decay.