The synergy is manifested both as increased antitumour
efficacy, as well as less side effects from the chemotherapy.
Testing of Antitumour
activity by potato disc assay
This study aims to evaluate the antitumour
and antioxidant properties of Moroccan Berberis vulgaris.
These findings raise the possibility that, during the evolution toward the more aggressive forms, epithelial cells in E-MpMs acquire immune properties as a result of a transdifferentiation process, which is probably a mechanism underlying the evasion from an ongoing antitumour
immune response .
We would like to highlight the phase III KEYNOTE-059 trial, as it showed antitumour
activity and durable responses in patients with advanced gastric/GEJ cancer progression after more than 2 lines of therapy.
The results showed that cardiotoxicity was reduced and antitumour
responses were increased, compared to free drug (Zeng et al.
effect was also observed with gamma irradiated M.
(6) ITK inhibition by ibrutinib is believed to shift the balance between Th1 and Th2 T cells and enhance antitumour
Yamada, Total Synthesis of an Antitumour
In this way, they possess antitumour
efficacy in addition to their targeted impact.
Accumulating lines of evidence have shown that API shows antitumour
activity and induces apoptosis in many cancer cell lines in a dose-dependent manner [21, 22].
Concomitant targeting of MDSCs may therefore increase the antitumour
activity of PD-1/PD-L1 inhibitors in nonresponders.