Despite advances in diagnostic technology and invention of new
antituberculous drugs, TB continues to remain a major public health concern.
She was treated as a case of intestinal tuberculosis and completed a nine month course of
antituberculous drugs.
Unlike pulmonary Kochs, osteoarticular tuberculosis should be treated with
antituberculous drugs for a longer duration, preferably for 18 months.
8] Many a times, due to lack of availability of bronchoscopy in rural areas, any radiological opacity related to malignancy not resolved with antibiotics considered as due to tuberculosis, which leads to unnecessary use of
antituberculous drugs and delays the diagnosis of cancer.
HLH has a well known association with disseminated tuberculous Mycobacterial infections; and even reported to occur following initiation of first line
antituberculous drugs such as rifampin and isoniazid.
Antituberculous drugs may vary in their ability to kill mycobacteria, depending on whether they are located in cavitary or closed caseous lesions or within the cells.
2] However, despite the availability of effective first-line
antituberculous drugs and large-scale rollout of antiretroviral therapy (ART), TB is still the most common opportunistic disease and main driver of mortality in HIV, causing up to 100 000 deaths in SA in 2012.
The condition should be kept in mind in a patient presenting with; recurrent sinusitis and bronchiectasis, asthma like symptoms and signs responding poorly to conventional treatment, recurrent lower respiratory tract infections causing fever, sweating and weight loss, tempting the physician to give a trial of
antituberculous drugs.
LV is treated with
antituberculous drugs similar to tuberculosis of any other organ.
7 Percent),
antituberculous drugs, cephalosporins and antiepileptics (6.
45) Because of the worsening global burden of MDR-TB and extensively drugresistant TB, methods that can be used to test for resistance to second-line
antituberculous drugs should receive emphasis for research and development as well as for clinical trials.
Extensive drug resistant tuberculosis (EXDR TB) was defined as multidrug resistant tuberculosis that is also resistant to at least three of the six classes of second line
antituberculous drugs.
