antitubercular


Also found in: Dictionary.

antitubercular

[-too͡bur′kyələr]
any agent or group of drugs used to treat tuberculosis. At least two drugs, and usually three, are required in various combinations in pulmonary tuberculosis therapy. These include isoniazid, ethambutol hydrochloride, streptomycin sulfate, and rifampin. Supplements of pyridoxine (vitamin B6) also may be needed to relieve the symptoms of peripheral neuritis that can occur as a side effect of isoniazid.

antitubercular

, antituberculous (ant?i-too-ber'kyu-lar) (kyu-lus) [ anti- + L. tubercle]
1. Preventing or treating tuberculosis.
2. An agent used to prevent or treat tuberculosis.
Synonym: antituberculotic
References in periodicals archive ?
Multidrug-resistant tuberculosis (MDR-TB) is a form of tuberculosis that occurs due to a strain of Mycobacterium tuberculosis that is resistant to at least isoniazid and rifampicin with or without any other first-line antitubercular drugs.
2 mL was inoculated into four tubes of Lowenstein-Jensen (LJ) medium each, containing potassium nitrate (1000 [micro]g/mL) & antitubercular drugs of specific concentration.
Sputum smear-negative tuberculosis was diagnosed on the basis of clinical symptomatology, chest X-ray findings, raised ESR and response to antitubercular chemotherapy.
Common drugs associated are cotrimoxazole, nevirapine and antitubercular drugs.
As per the RNTCP guidelines, category I antitubercular treatment was started.
Treatment: Patients with TB pleural effusion were treated with Antitubercular treatment.
Definite clinical and radiological improvement in 6 to 8 weeks after administration of antitubercular treatment.
This study included adults diagnosed and referred by collaborating department of treated pulmonary TB patients having completed Category I full course of antitubercular treatment [2[(EHRZ).
In these cases, MDR-TB shows additional resistance to the second-line antitubercular drugs.
She has been diagnosed with pulmonary tuberculosis (TB) and been on antitubercular treatment for over a month.
Effect of rifampicin-based antitubercular therapy on nevirapine plasma concentrations in South African adults with HIV-associated tuberculosis.
Biochemical studies on the plant methanolic, hexane and aqueous extracts show the presence of the quinoline alkaloid lunacridine to be effective against tropical ulcers [16], antitubercular [14] and antibacterial activity [17,18], graveolinine, 4-methoxy-2-phenylquinoline and kokusagine for antituberculosis activity [19], lunacridine and its trifluoroacetyl derivative for DNA intercalation, topoisomerase II decatenation, cytotoxicity and caspase activation activities [16] and Cytochrome P450 2D6 inhibitory effect [20].