Compounds R26, Q30, and M9 showed maximum
antitubercular activity (MIC: 62.5 [micro]g/mL).
Table 8 depicts
antitubercular treatment response of the patients within 3 months.
Based on the MDR and
antitubercular activities of 2-substituted benzothiazoles, it appears that this backbone is an excellent lead compound for the development of novel
antitubercular agents.
(10) They proposed that the mainstay of treatment should be early drainage and complete debridement of necrotic tissue, which may include sternectomy and concomitant with
antitubercular treatment (ATT).
Isolated tubercular liver abscess in an elderly diabetic successfully treated with systemic
antitubercular drugs.
To that end, an
antitubercular formulation including piperine was developed.
This study included adults diagnosed and referred by collaborating department of treated pulmonary TB patients having completed Category I full course of
antitubercular treatment [2[(EHRZ).sub.3]/4[(RH).sub.3]] supervised as per the RNTCP guidelines of India.
Tuberculous enteritis had been mostly eradicated in the United States due to improved standard of living, pasteurization of milk, control of bovine tuberculosis, and introduction of
antitubercular therapy [4].
Fifty molecules of 1,2,4-Triazole derivatives as potent
antitubercular agents that were used in this study were obtained from the literature [4].
Some hydrazone derivatives possessing a quinoline moiety have been well known as having a broad spectrum of biological activities such as antibacterial [1], anticancer [2],
antitubercular [3-5], antifungal [6], anti-inflammatory [7], antimalarial [8], and antimicrobial [9, 10].
Outpatient
antitubercular therapy consisted of isoniazid, rifampicin, and pyrazinamide for 4 months and subsequently isoniazid and rifampicin for 8 months.
She has been diagnosed with pulmonary tuberculosis (TB) and been on
antitubercular treatment for over a month.
