antitoxin


Also found in: Dictionary, Thesaurus, Legal, Encyclopedia, Wikipedia.

antitoxin

 [an´tĭ-tok″sin]
a particular kind of antibody produced in the body in response to the presence of a toxin; see also immunity. adj., adj an´titoxic.
botulism antitoxin an equine antitoxin against the toxins produced by the types A and B and/ or E strains of Clostridium botulinum; administered intravenously in the postexposure prophylaxis and treatment of botulism, other than infant botulism. Generally trivalent (ABE) antitoxin is used.
diphtheria antitoxin equine antitoxin from horses immunized against diphtheria toxin or the toxoid; administered intramuscularly or intravenously in the treatment of suspected cases of diphtheria.
equine antitoxin an antitoxin derived from the blood of healthy horses immunized against a specific bacterial toxin.
tetanus antitoxin equine antitoxin from horses that have been immunized against tetanus toxin or toxoid; used for the passive prevention and treatment of tetanus. It is rarely used, tetanus immune globulin being preferred.

an·ti·tox·in

(an'tē-tok'sin),
Antibody formed in response to antigenic poisonous substances of biologic origin, such as bacterial exotoxins (for example, those elaborated by Clostridium tetani or Corynebacterium diphtheriae), phytotoxins, and zootoxins; in general usage, antitoxin refers to whole, or globulin fraction of, serum from people or animals (usually horses) immunized by injections of the specific toxoid. Antitoxin neutralizes the pharmacologic effects of its specific toxin in vitro, and also in vivo if the toxin is not already fixed to the tissue cells.
[anti- + G. toxikon, poison]

antitoxin

(ăn′tē-tŏk′sĭn, ăn′tī-)
n.
1. An antibody formed in response to and capable of neutralizing a specific toxin of biological origin.
2. An animal or human serum containing antitoxins. It is used in medicine to prevent or treat diseases caused by the action of biological toxins, such as tetanus, botulism, and diphtheria.

antitoxin

Immunology An antibody-rich serum from an animal stimulated with specific antigens or bacterial toxins–eg, botulinus, tetanus or diphtheria, which is used to provide passive immunity. See Passive immunity.

an·ti·tox·in

(an'tē-tok'sin)
Antibody formed in response to antigenic poisonous substances of biologic origin (e.g., bacterial exotoxins, phytotoxins, and zootoxins); in general usage, serum from humans or animals (usually horses) immunized by injections of the specific toxoid. Antitoxin neutralizes the pharmacologic effects of its specific toxin.
[anti- + G. toxikon, poison]

antitoxin

An ANTIBODY formed by the immune system in response to the presence of TOXIN, produced by bacteria.

antitoxin

a type of ANTIBODY that neutralizes TOXINS.

Antitoxin

An antibody that is capable of neutralizing the specific toxin (a specific cause of disease) that stimulated its production in the body and is produced in animals for medical purposes by injection of a toxin or toxoid with the resulting serum being used to counteract the toxin in other individuals.

an·ti·tox·in

(an'tē-tok'sin)
Antibody formed in response to antigenic poisonous substances of biologic origin; in general usage, antitoxin refers to whole, or globulin fraction of, serum from people immunized by injections of the specific toxoid.
[anti- + G. toxikon, poison]
References in periodicals archive ?
Neutralization depends mainly on having all the specific antitoxins against a, p, e and iota toxins.
Restriction sites BamHI and XhoI were added at 5' and 3' end of PCR amplification of antitoxin gene (252 bp) product from genomic DNA using primer sets 1 and 5, respectively, for the directional cloning in pET28(a) vector to produce plasmid pJSL2.
If there were no antitoxin, the bacteria would kill itself," said Craig L.
The importance of obtaining a complete family history was critical to the physicians making a quick diagnosis and administering the antitoxin within 7 hours of admission.
Unfortunately, this rule proved to be far less predictive in the validation cohort, in which 26 patients had antitoxin A IgG data available.
He considers antitoxin (antibody) a normal component of the cell with special <<sidechains>> (Receptors) as part of the operational cellular apparatus.
"This vaccine would give antitoxin immunity [which] could help contribute to protection by combination vaccines," he says.
Because of their doctor's refusal to admit that they suffered from botulism, they did not receive antitoxin in time to lessen the severity of the damage to their bodies.
Whereas the toxin produced by isolates derived from mammalian botulism was neutralized only with type C antitoxin, the toxins of all isolates related to avian botulism were neutralized with both type C and D antitoxins.
Attached to these films are toxin or antitoxin antibody molecules.
DOD gave HBI additional $2.2 MM in FY 03 (part of Tripler Hospital funding) to test HBI's anthrax antitoxin compounds further; Sen.
"The hypothesis was that if grass sickness was caused by intoxication with bacillus botulinus, then the blood in the serum of chronic cases should contain traces of antitoxin," explains Bruce McGorum of the University of Edinburgh.