treatment for graves' disease in children: a long-term retrospective study at a single institution.
The American Thyroid Association (ATA)/American Association of Clinical Endocrinologists (AACE) 2011 and The ATA 2016 guidelines recommended methimazole (MMI) for the first line antithyroid drug
in the treatment of Graves' hyperthyroidism in nonpregnant patients [1, 2].
Keywords: Antenatal, Antithyroid drug
, Hyperthyroidism, Hypothyroidism, Thyroid cancer, Thyroid nodules, Lactation.
Although antithyroid drug
therapy is still the first-line treatment of Graves' hyperthyroidism in children in many European countries, radioactive iodine treatment in the USA is often used in children aged 10 years and older.
Abbreviations anti-Tg: hyroglobulin antibodies anti-TPO: hyroid peroxidase antibodies ATD: Antithyroid drug
CS: Cowden syndrome FNA: Fine needle aspiration fT3: Free triiodothyronine fT4: Free thyroxine GD: Graves' disease IQ: Intelligence quotient NCCN: National Comprehensive Cancer Network PTEN: Phosphatase and tensin homolog RAI: Radioiodine TRAbs: hyrotropin receptor antibodies TSH: hyrotropin.
To the best of our knowledge, the current study represents the first report that studies the effect of a well-known antithyroid drug
, PTU, and T4 usage recovery not only on T4-induced hemodynamic alteration (e.g., BP) but also on cardiac hypertrophy and altered responses of the contractile myocardium both in vivo at the whole heart level and ex vivo at the cardiac tissue level.
During antithyroid drug
therapy, they noticed marker improvement .
Beta-blockers often are added as adjunct therapy in the initial phases of antithyroid drug
treatment to control cardiac symptoms (e.g., tachycardia) of hyperthyroidism (Bartalena, 2013).
French Childhood Graves' Disease Study Group Predictors of autoimmune hyperthyroidism relapse in children after discontinuation of antithyroid drug
The substance is historically relevant in the preparation of antithyroid drug
. Sulfhydryl compounds are known to undergo electrochemical oxidation at solid electrodes, but their oxidation occurs at relatively high potentials [1, 2].
(ATD) therapy of Graves' hyperthyroidism is in many patients followed by a remission of the autoimmunity of GD with a gradual disappearance of TRAb from the circulation .