On the other hand, the high levels of antithyroglobulin antibody
(anti-TgAb) may cause Tg levels to be erroneously low.
Furthermore, this study only measured TPOAb value and did not included other autoantibodies like Antithyroglobulin antibody
, TSH Receptor Antibody in assessing thyroid autoimmunity
Table 2: The sensitivity and specificity of anti-TPO and antithyroglobulin antibody
At this time, the serum thyroglobulin level was 290 ng/mL (immunometric assay) and antithyroglobulin antibody
level was 8.07 U/mL (quimioluminescence assay).
We could observe that as lymphocytic infiltrate (Figure 1) in GD becomes more pronounced, the frequency of antibody positivity (Figure 2) increases and, in the case of antithyroglobulin antibody
, it was significant: those with negative lymphocytic infiltrate did not have antibody positivity and among those with severe lymphocytic infiltrate, all had antibody positivity (p = 0.0003).
In the 2012 edition (76 laboratories, 17 679 195 inhabitants), the final report suggested some recommendations to improve the request appropriateness of aspartate aminotransferase (AST), antigliadin antibody (AGA), antithyroglobulin antibody
(TgAb), total bilirubin (TBIL), [gamma]-glutamyltransferase (GGT), iron, free thyroxine (FT4), erythrocyte sedimentation rate (ESR), and urea tests, with a list of testreduction strategies that worked in primary care facilities.
Antithyroid antibody levels were elevated (antithyroglobulin antibody
: 717.2 IU/mL, TSHR antibody: 20.98 U/L); thyroid hormones and B lymphocytes were within normal range.
titer was elevated (1:500; normal less than 1:100).
However, the serum thyroglobulin remained less than 5.0 ng/ml and antithyroglobulin antibody
was the same at 14.2, and antimicrosomal antibody was decreased, but still elevated (23.9) We advised her to continue the regimen of the Calcarea iodata.
Thyroid function tests were as follows: TSH: 9.75 [micro]lU/mL (0.35-0.9[micro]lU/mL); T4: 0.67 pg/dL (4.87-11.72 [micro]g/dL) with positive antithyroid antibodies (antithyroglobulin antibody
, 4.84 lU/mL, antiperoxidase antibody, 1000 lU/mL).
The evolution of the ophthalmopathy during antithyroid drug therapy and its relationship with serum thyroglobulin and antithyroglobulin antibody
in patients with Basedow's disease.