Four proteins (antithrombin-III, transmembrane and immunoglobulin domain-containing protein 1, tumor protein D52, and thymidine phosphorylase) are associated with different types of cancers (p = 4.17 x [10.sup.-4] - 3.21 x [10.sup.-2]), while 2 proteins (antithrombin-III and thymidine phosphorylase) are associated with organism injury and abnormalities (p = 8.35 x [10.sup.-4] - 4.54 x [10.sup.-2]).
Thirty-four proteins in our study have been reported as constituents of the normal urine, while 11 proteins (antithrombin-III, alpha-amylase 1, U3 small nucleolar RNA-associated protein 18 homolog, thymidine phosphorylase, endonuclease domain-containing 1 protein, E3 ubiquitin-protein ligase rififylin, quinone oxidoreductase-like protein 1, interleukin enhancer-binding factor 2, transmembrane and immunoglobulin domain-containing protein 1, Ras-related protein Rab-36, and Tumor protein D52) were not reported in the normal urine proteome .
* Antithrombin-III. Antithrombin-III (AT-III) is a natural occurring inhibitor of blood coagulation and plays an important part in maintaining blood in the fluid state.
Fully automated antithrombin-III assays by synthetic substrate on the Multistat III.