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(an'tē-strep-tol'i-sin), Avoid the mispronunciation antistreptoly'sin.
An antibody that inhibits or prevents the effects of streptolysin O elaborated by group A streptococci; the amount of antistreptolysin in the serum is frequently increased during and after streptococcal disease, and comparative titers may aid a diagnosis and prognosis.
Farlex Partner Medical Dictionary © Farlex 2012


(an″tī-strep-tŏ-lī′sĭn) [ anti- + streptolysin]
An antibody that opposes the action of streptolysin.

antistreptolysin O

Abbreviation: ASLO
An antibody against streptolysin O that is used retrospectively to diagnose infections with group A beta-hemolytic streptococci.
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
Johnson, "Antistreptolysin O and anti-deoxyribonuclease B titers: normal values for children ages 2 to 12 in the United States," Pediatrics, vol.
Blood count, sedimentation rate, biochemical parameters, protein electrophoresis, levels of immunoglobulin, complement, antistreptolysin O, C-reactive protein, rheumatoid factor, anti-nuclear antibody, anti-deoxyribonucleic acid levels, tumor markers, and thyroid function tests were all within normal limits.
The following blood tests were also performed: liver function tests; blood lipid levels; immunoglobulin (IG) G (IgG), IgM, IgA, antistreptolysin O, rheumatoid factor, complement C3 and complement C4 levels; testing for the presence of antinuclear antibodies (ANAs), anti-double stranded-DNA antibodies, anti-phospholipase A2 receptor antibodies, c-anti-neutrophil cytoplasmic antibodies, and p-anti-neutrophil cytoplasmic antibodies; the ratio of blood monospecific free light chain; immunoassay electrophoresis; and hepatitis B and C serology.
Optilite assays currently include: Freelite[R] serum free light chain assays, IgG subclasses (lgG1-lgG4), IgG, Low Level IgG (CSF/urine) IgA, IgA Subclasses (lgA1-lgA2), IgM, IgD,' Acid Glycoprotein, Albumin, Low Level Albumin (CSF/urine), Antistreptolysin O, Beta-2Microglobulin, Ceruloplasmin, CH50, Cystatin C, C3c, C4, CI inactivator, Haptoglobin, Hevylite IgA Kappa, Hevylite IgA Lambda, Hevylite IgM Kappa, Hevylite IgM Lambda, Apo A1, Alpha-2-Macroglobulin, Prealbumin, Transferrin
All patients were admitted to the hospital and received the following routine laboratory tests, including ESR, C-reactive protein (CRP), antistreptolysin O (anti-"o"), and HLA-B27; preoperative studies such as anteroposterior and lateral views of X-rays of the cervical spine, CT scan with 3-dimensional reconstruction, and MRI were completed.
Hematological tests are as follows: erythrocyte sedimentation rate (ESR), c-reactive protein (CRP), rheumatoid factor (RF), antistreptolysin (ASO), antinuclear antibodies (ANA), extractable nuclear antigen (ENA), antineutrophil neutrophil cytoplasmic antibody (ANCA), toluidine red syphilis serum test (TRUST), treponema pallidum specific antibodies (TPPA), and aquaporin 4 antibody (AQP4-IgG) were performed.
Among all patients with EN, 19 (23.4%) had recent upper respiratory tract infections and 13 (16%) of them had serological evidence for streptococcal pharyngitis (a positive throat swab culture for Streptococcus pyogenes in one patient and high antistreptolysin O titers in the others).
Serial antistreptolysin O titres showed a rising trend, eventually rising to 540 IU/[micro]L from 220 IU/[micro]L.
The patient's hemoglobin level was 8.3 g/dL and hematocrit was 25.8%; all other biochemical, serologic and rheumatologic test results were normal (antistreptolysin O, C-reactive protein, and rheumatoid factors were within reference ranges; antinuclear antibody, anti-DNA, and human leukocyte antigen B27 tests were negative; no positive results were returned for cytomegalovirus, toxoplasma, herpes simplex virus, hepatitis B or C, human immunodeficiency virus, Salmonella, Brusella, Lyme disease and syphilis tests).
CS: YBOCS-Compulsion Sub-score; OS: YBOCS-Obsession Sub-score; TS: YBOCS-Total Score; ASO: Antistreptolysin Serum Titers; CRP: C-reactive protein; 25-(OH) D: 25-hydroxyvitamin D; PTH: parathormone; ALP: alkaline phosphatase Table 4.
Urinalysis, urine culture, and Strep Antistreptolysin O Titers laboratory findings were negative.
Liver and renal function tests and urinalysis, peripheral blood smear and levels of antistreptolysin O, markers for hepatitis B and C, anti-HIV antibodies, Brucella and Salmonella, and chest X-ray and abdominal ultrasonography were within normal ranges.