antiserum

(redirected from antisera)
Also found in: Dictionary, Thesaurus, Encyclopedia.
Related to antisera: Monoclonal antibodies

antiserum

 [an´tĭ-se″rum]
1. a serum containing antibodies, such as one obtained from an animal that has been subjected to the action of antigen either by injection into the tissues or blood or by infection. See also immunity and immunization. Called also immune serum.
2. a reagent source of antibody, often sold commercially.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

an·ti·se·rum

(an'tē-sē'rŭm),
Polyclonal serum that contains demonstrable antibody or antibodies specific for one (monovalent or specific antiserum) or more (polyvalent antiserum) antigens; may be prepared from the blood of animals inoculated with an antigenic material or from the blood of animals and people who have been stimulated by natural contact with an antigen (as in those who recover from an attack of disease).
Synonym(s): immune serum
Farlex Partner Medical Dictionary © Farlex 2012

antiserum

(ăn′tĭ-sîr′əm)
n. pl. anti·serums or anti·sera (-sîr′ə)
Human or animal serum containing antibodies that are specific for one or more antigens.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

antiserum

Immunology A serum that contains Igs against specified antigens, used therapeutically
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

an·ti·se·rum

(an'tē-sēr'ŭm)
Serum that contains antibody or antibodies specific for one or more antigens; may be prepared from the blood of animals inoculated with an antigenic material or from the blood of animals and people who have been stimulated by natural contact with an antigen (as by an attack of disease).
Synonym(s): immune serum.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

antiserum

Animal or human blood serum which contains ANTIBODIES to infective organisms or to the TOXINS produced by organisms. The serum donor must previously have been infected with the organisms concerned.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

antiserum

see SERUM.

antiserum

) antitoxin containing large quantities of ANTIBODIES to a specific ANTIGEN, which confers quick-acting ‘passive’ IMMUNITY when donated to an individual who may have been exposed to the antigen. For example, tetanus antiserum is injected after the possible entry of tetanus bacterium in an accident. Compare VACCINE.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
References in periodicals archive ?
Specificity of local antigen: The best working dilution of each antigen were also tested to check the specificity of local antigens using known antisera of Mycoplasma gallisepticum and Mycoplasma synoviae(Charles River, USA).
Compared with the negative controls, the PR of Charybdi japonica antisera with C.
* Heavy-chain-only results often are artifacts that require additional testing to reveal the light-chain component; additional tests that may be used include sample pretreatment with a reducing agent before IFE, IFE with different antilight-chain antisera (or the same antisera with a different dilution of serum), capillary zone electrophoresis with immunosubtraction, IgA Hevylite testing, and MALDI-TOF-MS.
After immunization, the obtained antisera were tested for their ability to specifically recognize the VWF enriched from plasma samples of human healthy donors.
Method controls to validate the specificity of the binding of immunocytochemical reagents with tissue included: 1) omission of the primary antiserum, 2) replacement of the primary antiserum with nonimmune serum, 3) dilution profile of the primary antiserum using doubling dilutions on serial sections, 4) influence of the salt content (up to 0.5 m) of the buffer, and 5) complement-deprived antisera. In addition, controls for the specificity of double labeling were performed as follows: 1) using nonimmune serum as the first layer, and 2) using the labeled antisera without the presence of one or both primary antisera.
One drop of each of the eight polyvalent antisera and a drop of phosphate buffered saline were placed on a partition of the slide.
We isolated immunoglobulin G (IgG) from rabbit antisera using a two-step procedure as described by McKinney and Parkinson (8).
These products, which include antisera, agglutination reagents, latex reagents and stained suspensions, are presently manufactured by Murex, an Abbott subsidiary.
Fourteen (56%) of the 25 analyzed artifacts react positively to six animal antisera and to human blood.