antisense compound


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Related to antisense compound: Antisense therapy, antisense DNA

antisense compound

Any of the manufactured compounds that may alter disease processes by blocking the production of harmful proteins by diseased cells. These molecules seek out and impede the functioning of a diseased cell's messenger RNA (a “sense” strand). Without this intervention, the RNA would carry basic directions for the production of disease-causing proteins. Synonym: antisense drug
See also: compound
References in periodicals archive ?
Early research by Isis indicated that an antisense compound would prove effective against CMV if it homed in on one of the messenger RNAs that help produce the series of proteins CMV needs for replication.
He hopes to begin human clinical trials of antisense compounds within two years.
M2 EQUITYBITES-August 2, 2012-Isis Pharmaceuticals Inc publishes encouraging new preclinical data evaluating antisense compounds to treat myotonic dystrophy type 1 (DM1)(C)2012 M2 COMMUNICATIONS http://www.
Like a key in a lock, NEUGENE antisense compounds are designed to match up perfectly with a specific gene or viral sequence, blocking the function of the target gene or virus.