antisense DNA


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an·ti·sense DNA

the strand of DNA complementary to the one bearing the genetic message and from which it may be reconstructed; a DNA sequence complementary to a portion of mRNA; used as potential therapeutic agent to stop transcription or translation of pathogens or inappropriately expressed host gene.
References in periodicals archive ?
Under the terms of the sponsored research agreement, the company said DNAbilize antisense DNA technology will be investigated for the development of a brain cancer immunotherapy that works by activating the patient's own immune system to fight their cancer.
On the other path, biochemists are synthesizing small pieces of antisense DNA in the laboratory that match known sequences of DNA.
He delivered the first successful antisense attack against a virus by adding small pieces of synthesized antisense DNA to a cell culture to block the RNA of the virus causing Rous sarcoma, a cancer of chickens.
MG98 -- A 2nd generation antisense DNA compound, currently in Phase II in various cancers.
He also made the first presentation entitled, "Molecular Consequences of Antisense DNA and RNA Knockout of Bcl-2 and Bclxl.
He will also make the first presentation entitled "Molecular Consequences of Antisense DNA and RNA Knockout of Bcl-2 and Bclxl.
The company also announced that it has increased the depth of its HIV/AIDS treatment pipeline to include two proprietary HIV-Hemopurifier(TM) treatments: AEMD-45, which is an immobilized antibody treatment cartridge, and AEMD-61, a treatment cartridge that immobilizes both antibodies for HIV and antisense DNA.
Our objective will be to develop further the ability of Transcell's permeation enhancers to transport antisense DNA compounds across both cellular and mucosal membranes to specific sites within the cell so as to facilitate their potential applications as anti-HIV and anti-AIDS treatments," added Tallett.