antirheumatic


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antirheumatic

 [an″te-, an″ti-roo-mat´ik]
counteracting rheumatism and rheumatoid disease.

an·ti·rheu·mat·ic

(an'tē-rū-mat'ik), Although the digraph rh occurring at the beginning of a syllable in a word of Greek origin is ordinarily changed to rrh when a prefix or other lexical element is placed before it, the r is not doubled in this word.
1. Denoting an agent that suppresses manifestations of rheumatic disease; usually applied to antiinflammatory agents or agents that are capable of delaying progression of the basic disease process in inflammatory arthritis.
2. An agent possessing such properties (for example, gold compounds).

antirheumatic

Any treatment for, or prophylaxis against, any form of rheumatism.
References in periodicals archive ?
The efficacy and safety of Taltz in AS was demonstrated in two randomized, double-blind, placebo-controlled Phase 3 studies that included 657 adult patients with active AS: COAST-V in patients who are biologic disease-modifying antirheumatic drug (bDMARD)-naive and COAST-W in patients who previously had an inadequate response or were intolerant to tumor necrosis factor (TNF) inhibitors.
Among the 25 transplanted patients, none died during the extended follow-up, 2 experienced cardiac failure, and 23 remained off of any disease-modifying antirheumatic drugs.
Methotrexate is the first-line disease-modifying antirheumatic drug used in patients with RA (Annals of the Rheumatic Diseases, September 2017).
In the last decade, there have been significant advances in the treatment of RA, especially for patients whose arthritis does not respond to conventional disease-modifying antirheumatic drugs (DMARDs).
According to the company, the SPIRIT-P1 study evaluated the safety and efficacy of Taltz compared to placebo in patients with active PsA who had never been treated with a biologic disease-modifying antirheumatic drug.
The findings are encouraging because patients with rheumatoid arthritis have a higher risk of developing shingles than other adults, and tofacitinib and certain other disease-modifying antirheumatic drugs are thought to further increase this risk.
Most participants in the study had longstanding RA and were taking disease-modifying antirheumatic drugs.
A human monoclonal antibody, Kevzara is indicated for use in patients who have had an inadequate response or intolerance to one or more disease-modifying antirheumatic drugs (DMARDs), such as methotrexate (MTX).
The average duration of RA among all participants was 17 years, and 58 percent of the participants were taking a disease-modifying antirheumatic drug, such as methotrexate, sulfasalazine (Azulfidine), and hydroxychloroquine (Plaquenil).
Researchers compared the health records of more than 11,000 RA patients taking TNFis with the records of about 3,000 RA patients taking synthetic disease-modifying antirheumatic drugs (sDMARDs), another common RA treatment.
In this comprehensive review of 3,742 relevant publications, there was general agreement that initial treatment should center on disease-modifying antirheumatic drugs (DMARDs) plus systemic glucocorticoids.
Editor's Note: The authors remark that MK-7 is significantly less toxic than antirheumatic drugs and it has the additional benefit of protecting against osteoporosis.