In this way the researchers could pinpoint year of starting
antiretrovirals as an individual death risk factor--regardless of whatever other risk factors a person had.
The scientists found that, compared to
antiretrovirals alone, the addition of the immunotoxin significantly reduced both the number of HIV-infected cells producing the virus in multiple organs and the level of HIV in the blood.
Antiretroviral therapy may greatly reduce the risk of HIV-1 transmission, according to a study of serodiscordant heterosexual couples in seven African countries.
This is a very important potential drug, but it must be used in combination with other active
antiretrovirals.
We describe a severely immunosuppressed HIV-1-positive man in whom immune restoration disease associated with pulmonary infection caused by Mycobacterium microti developed after
antiretroviral treatment.
To determine the current magnitude of that problem, researchers at the Centers for Disease Control and Prevention in Atlanta estimated how many people nationwide are receiving
antiretroviral drugs and how many others could benefit from them.
An improvement in liver histology may increase the capacity to tolerate
antiretroviral agents, prophylactic drugs, medications used to treat other co-morbid conditions, and complications of
antiretroviral therapy.
When the researchers did not count temporary viral load blips followed by an undetectable load without a change in
antiretrovirals, rebound rates were 5.
Some of the patients in the trials already had cross resistance to Prezista when the trial began (due to their extensive resistance to other protease inhibitors), and it got worse on the average, as they used the drug--showing the importance of having more than one active
antiretroviral, instead of introducing new drugs one by one as they become available, and then often losing them to resistance.
Because of these limitations, HIV researchers are exploring alternative treatment strategies, such as "structured treatment interruptions" (STIs), by using a variety of dosing schedules,
antiretroviral regimens, and patient populations.
