5) Typically, an antiretroviral
regimen is changed only after it fails.
therapies now combine multiple individual drugs to reduce the amount of virus in a person's body.
The researchers divided study participants into three groups, depending on when they started antiretroviral
The research team then used accepted statistical methods to learn three things: (1) individual factors linked to having a viral load rebound, (2) viral rebound rate according to several key factors including age, year starting antiretroviral
therapy, and time since starting antiretroviral
therapy, and (3) probability of viral rebound from year to year in a 35-year-old man who started antiretroviral
therapy after 2008.
The total cost of home-based testing and initiation of antiretroviral
treatment was US$20,005, or US$172 per participant who initiated home care.
The new WHO guidelines also recommend providing antiretroviral
therapy to all children younger than 5, all pregnant and breastfeeding women with HIV, and all HIV-positive patients with partners who are not infected, regardless of a person's T-cell count.
In Namibia, which has an 18% adult HIV prevalence rate, antiretroviral
treatment is free of charge at public-sector clinics.
It is interesting to note that while early initiation of antiretroviral
therapy was prominent on the programmes of all the international conferences last year, arguments against early initiation were distinctly lacking.
20 Gardner LI, Holmberg SD, Moore J, Use of highly active antiretroviral
therapy in HIV-infected women: impact of HIV specialist core.
concentrations in breast-feeding infants of women in Botswana receiving antiretroviral
therapy with efavirenz, zidovudine, and lamivudine was initiated at the correctional facility to treat his primary HIV infection.
Earlier this year, UNICEF estimated that no more than 25,000 of these children (about 1%) currently receive antiretroviral