antiresorptive

antiresorptive

(ant?i-re-sorp'tiv, -zorp') [ anti- + L. resorbere, to suck in]
1. Blocking or opposing the destruction of bone by osteoclasts.
2. An agent that prevents or slows the progress of osteoporosis. See: osteoporosis
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References in periodicals archive ?
Recommendations from the Endocrine Society in March 2019, a 2017 position statement from the European Calcified Tissue Society, and guidelines from other groups advise giving antiresorptive treatment (bisphosphonates, hormone therapy, or selective estrogen-receptor modulators) but do not say which one, in what dose, when, or for how long
Bisphosphonate before denosumab may avert BMD rebound
While effective, teriparatide is significantly more expensive than antiresorptive osteoporosis drugs, partially because there hasn't been competition, the review authors noted--until now.
Bone-Building Meds Battle Osteoporosis: These drugs stimulate new bone growth, making them powerful weapons against advanced osteoporosis
Most are antiresorptive drugs that slow down the activity of cells that break down old bone, while anabolic drugs stimulate cells that build new bone.
Getting to the bones of osteoporosis ... Almost three million Brits have osteoporosis - a condition which weakens the bones - and an estimated 500,000 fractures occur because of the condition every year. MICHELE O'CONNOR reveals what you need to know about your bones
Although there is actually no study showing that such a strategy would prevent the risk of vertebral fractures, several authors and medical societies advocate, at denosumab discontinuation, for a period of treatment with a bisphosphonate or another antiresorptive agent (estrogens or SERMs) to preserve BMD gain and avoid the risk of vertebral fracture [7, 11, 12].
Raloxifene Has No Efficacy in Reducing the High Bone Turnover and the Risk of Spontaneous Vertebral Fractures after Denosumab Discontinuation
We used a similar array of implants in both groups, although more adjuvants tended to be given to patients receiving antiresorptive therapy.
Comparison of Atypical and Osteoporotic Femoral Shaft Fractures in the Elderly: A Multicenter Study
There have been reports of AFF with denosumab which is another antiresorptive agent (8,9).
Bilateral Incomplete Atypical Femoral Fracture due to Long-Term Bisphosphonate Use: A Case Report/Uzun Sureli Bifosfonat Kullanimina Bagli Olarak Gelisen Bilateral Inkomplet Atipik Femur Frakturu: Bir Olgu Sunumu
Finally, genetic evidence from mice with osteoclast-specific AR deletion indicates that androgen signaling in osteoclasts plays no role in the antiresorptive effect of androgens on the cancellous or cortical bone compartments [17].
A Case of Male Osteoporosis: A 37-Year-Old Man with Multiple Vertebral Compression Fractures
and Taisho Pharmaceutical Co., Ltd., announced today that Chugai filed a new drug application to the Ministry of Health, Labour and Welfare for the oral formulation of bisphosphonate antiresorptive agent which was co-developed by the two companies for the indication of osteoporosis.
Japan : New Drug Application Filed for Ibandronate Sodium Hydrate Oral Agent, Bisphosphonate Antiresorptive Agent
A position paper on Medication Related Osteonecrosis of the Jaw (MRONJ), released by the American Association of Oral and Maxillofacial Surgeons, expands the scope of the condition previously referred to as Bisphosphonate-Related Osteonecrosis of the Jaw (BRONJ) and changes its name to reflect the antiresorptive (denosumab) and antiangiogenic therapies that have recently been associated with the condition.
AAOMS issues position paper expands scope of Medication-Related Osteonecrosis of the Jaw (MRONJ)
It is also the most widely prescribed antiresorptive for treatment of osteoporosis globally and has been clinically studied for over 18 years.
Challenges and opportunities in managing osteoporosis care
In recent years there has been increased interest in the effects of antiresorptive therapies on trabecular architecture.
Effects of zoledronic acid on physiologic bone remodeling of condylar part of TMJ: a radiologic and histomorphometric examination in rabbits
The prescription drugs approved for the treatment of fracture prevention are often classified by whether they reduce bone loss (antiresorptive) or promote bone growth (Table 1).
Current treatment approaches to osteoporosis--2013

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