To address complications for the recipient, including the necessity to continually take antirejection
, or immunosuppressive, medications, our recommendation to patients who undergo uterus transplantation surgery is to remove the uterus after delivery of 2 babies.
The patient did not experience any acute rejection during follow-up and no antirejection
therapy was required.
Ken continues to take antirejection
medication twice a day, but says that other than that his life is completely normal.
The determined young girl, who will need antirejection
drugs for the rest of her life, has now rejoined her classmates and is back to her lively self.
And although she is required to take antirejection
drugs and regular injections of haemoglobin, her new heart has never let her down.
Arthur continues to receive stem cell treatments from his veterinarian, and he takes a second antirejection
medication, mycophenolate, to help his body accept his new kidney.
Other than taking antirejection
medications to suppress his immune system so that it doesn't reject his new heart, his recovery has been trouble free.
The side effects of antirejection
drugs are very hard to live with.
Soon, better antirejection
drugs allowed strangers to donate and receive organs.
These conditions include HIV infection with CD4 count < 100 cells/microL, primary immunodeficiency or other immunosuppressive disorders, use of immunosuppressive medications such as glucocorticoids, antirejection
therapies in solid organ transplant recipients, TNF-alpha inhibitor therapies, and extremes of age.
Sernova believes its Sertolin technology has the potential to reduce or eliminate the need for expensive lifelong daily antirejection
drug cocktails that make subjects susceptible to serious infections.
Following transplantation, ART was recommenced on day 1 or day 2 and all patients received antithymocyte globulin or thymoglobulin induction therapy and an antirejection
regimen consisting of mycophenolate mofetil, tacrolimus and prednisone.