antipyrine


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antipyrine

 [an″te-, an″ti-pi´rēn]
a compound formerly used as an analgesic and antipyretic, now replaced by safer and more effective agents. Its current uses are as a component of multi-ingredient ear drop solutions and complexed with chloral hydrate in dichloralphenazone, a sedative and hypnotic used for headaches. Called also phenazone.

an·ti·py·rine

(an'tē-pī'rin),
An analgesic and antipyretic, no longer used systemically because of the risk of agranulocytosis. It is still used topically as an analgesic in acute otitis media and to loosen cerumen from the external auditory canal and as an analgesic following removal of cerumen.

an·ti·py·rine

(an'tē-pī'rin)
An analgesic and antipyretic, used topically as an analgesic in acute otitis media and to loosen cerumen from the external auditory canal.
References in periodicals archive ?
Inhibition of cyclooxygenase 3 (COX-3), a variant of COX-1, by analgesic/antipyretic drugs with low anti-inflammatory activity such as dipyrone (including its MAA metabolite) and antipyrine may possibly be the primary CNS mechanism for the reduction of pain (12).
Nevertheless, our results demonstrate that passive diffusion is not the key mechanism under lying placental translocation of PS particles because concentration equilibrium was not achieved after 4-6 hr compared with the passively transported antipyrine. According to Fick's law, diffusion of a substance depends mainly on the permeability of the membrane for the specific substance, the concentration gradient across the membrane, and the membrane surface area.
[10] NSAIDS like phenazone (Antipyrine), Metamizole and barbiturates as revealed by some older studies as most frequent agents, not widely used now a days.
Dyes Food Parameters Domestic Textile Dairy Yeast Fruits & sewage industry industry industry vegetable canning pH 7 6.5 4 5-7 5.5 TDS (mg/L) 500 17,000 19,000 5,000 1,270 T.S.S (mg/L) 220 1,800 12,150 1,000 2,200 COD (mg/L) 500 1,500 21,100 3,400 1,400 BOD (mg/L) 250 840 14,000 3,500 800 Oil & Grease 100 155 320 9 94 [Cl.sup.-] 50 -- -- -- -- (mg/L) Fabrics Pharma Parameters Beverage Fish Vit B(complex), industry canning Antipyrine, Anti TB, Alcoholates pH 9 11 6-10 1 TDS (mg/L) 1,290 8,218 500-3,000 86,000 T.S.S (mg/L) 760 565 -- -- COD (mg/L) 1,150 2,350 100-2,000 19,700 BOD (mg/L) 620 890 300-1,200 13,000 Oil & Grease -- 290 -- -- [Cl.sup.-] -- -- 100-300 18,500 (mg/L)
Ashour, "Design and synthesis of some thiazolyl and thiadiazolyl derivatives of antipyrine as potential non-acidic anti-inflammatory, analgesic and antimicrobial agents" Bioorganic and Medicinal Chemistry, vol.
1963 "Manifeste de Monsieur Antipyrine", en Sept manifestes Dada lampisteries.
Abstract Fixed drug eruption was first described by Brocq in 1894 in association with antipyrine therapy.
The higher drug metabolizing enzyme activities in the liver and other organs of horses have been linked with fast elimination of KTP like antipyrine, ampicillin (Elsheikh, 1997), sulphadimidine (Nouws et al., 1988), isometamidium (Wesongah et al., 2004) and meloxicam (Mehmood et al.,2011) in goats as compared to other species.
Estimation of plasma phosphate by determination of hydrolyzes phenol a with amino antipyrine. J.
Estimation of plasma phosphatase by determination of hydrolysed phenol with amino antipyrine. J.
A coupled HPLC - NMR method has been used for the detection and identification of ibuprofen, fluribiprofen, antipyrine and paracetamol [4].