antipsychotic drug


Also found in: Dictionary, Thesaurus.
Related to antipsychotic drug: schizophrenia, antidepressant drug

antipsychotic drug

n.
Any of a group of drugs, such as the phenothiazines or butyrophenones, that are used to treat psychosis. Also called major tranquilizer.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

antipsychotic

adjective Referring to an antipsychotic drug.

noun Any drug that attenuates psychotic episodes.
 
Agents
Phenothiazines, thioxanthenes, butyrophenones, dibenzoxazepines, dibenzodiazepines, diphenylbutylpiperidines.
 
Main types of antipsychotics
Typical and atypical, which differ in their side/adverse effects.
 
Indications
Management of schizophrenic, paranoid, schizo-affective and other psychotic disorders; acute delirium, dementia, manic episodes (during induction of lithium therapy), control of movement disorders (in Huntington’s disease), Tourette syndrome, ballismus, intractable hiccups, severe nausea and vomiting (by blocking the medulla’s chemoreceptor trigger zone).
 
Adverse effects
Extrapyramidal effects (dystonia, akathisia, parkinsonism), tardive dyskinesia due to blocking of basal ganglia; sedation and autonomic side effects (orthostatic hypotension, blurred vision, dry mouth, nasal congestion and constipation) are due to blocking of histaminic, cholinergic and adrenergic receptors.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
Iloperidone: A new benzisoxazole atypical antipsychotic drug. Is it novel enough to impact the crowded atypical antipsychotic market?
The condition is currently treated with antipsychotic drugs, but this therapy is given without guidance from lab tests to show effectiveness, as is common in other areas of medicine.
It seems that olanzapine, an antipsychotic drug regularly prescribed, is less likely to cause TdP.
In WE-D, which is considered as a subtype of TD, abnormal movements in the neck, face, mouth, arms, and legs appear shortly after a rapid reduction of the antipsychotic drug dose or sudden discontinuation of the drug in a portion of patients who do not display abnormal involuntary movements during antipsychotic treatment.
Non-Hispanic black children in counties without any child psychiatrists were significantly more likely to receive an atypical antipsychotic drug, compared with other racial and ethnic groups (12.1% vs.
Jick, "Antipsychotic drug use and risk of first-time idiopathic venous thromboembolism: a case-control study," The Lancet, vol.
Cognitive impairment, in particular, has an important impact on functional outcomes, and is not effectively treated by current antipsychotic drugs. Drugs acting at neurotensin receptors (e.g., PD149163) in the brain have become a new approach to potentially treating schizophrenia, but the effects these drug have on cognition have yet to be thoroughly investigated.
Antipsychotic drugs are used to treat schizophrenia and related disorders, acting on the central nervous system to modify neuronal function.
Otsuka Pharmaceutical is known for its antipsychotic drug Abilify, soft drink Pocari Sweat and health food Calorie Mate.