randomization stopped because the results showed a "surprising," statistically significant increased rate of all-cause mortality and major hemorrhages in patients treated with dual antiplatelet
Esomeprazole did not interfere with clopidogrel's antiplatelet
action when the two drugs were taken 14-16 hours apart every day, said Dr.
Patients without drug-eluting stents requiring antiplatelet
Nor are there "clear data" on the potential antiplatelet
effects associated with chronic use of ibuprofen at doses above 400 mg.
In three of these cases, patients had stopped their antiplatelet
medications before surgery.
developer of the market-leading VerifyNow([R]) System, the first rapid and easy-to-use point-of-care system for measuring platelet reactivity to antiplatelet
agents, today announced the release of the 2012 Update to the Society of Thoracic Surgeons (STS) Guideline on Use of Antiplatelet
Drugs in Patients Having Cardiac and Noncardiac Operations.
Factors that facilitate the prevention of stent thrombosis include suitable operation procedures, appropriate stent material and technique, and antiplatelet
agents, which particularly play a major role in preventing stent thrombosis.
The patient routinely received dual antiplatelet
therapy (aspirin and clopidogrel) but did not receive proton pump inhibitor (PPI) and gastric mucosal protective agent.
They also evaluated concomitant use of NSAIDs and antiplatelet
Most of the patients were pre-treated with antiplatelet
therapy, but 6,964 were not.
drugs are effective in preventing recurrence of atherosclerosis in type 2 diabetic patients.
The most recent dual antiplatelet
guidelines from the Dallas, Texas-based American Heart Association, and the American College of Cardiology, encourage healthcare providers to take a customized approach to treating patients with coronary artery disease, the organization said.