antineutrophil cytoplasmic antibodies

antineutrophil cytoplasmic antibodies (ANCA),

autoantibodies found in some autoimmune diseases, recognized by their reactivity with cytoplasmic antigens in neutrophils; two groups are recognized: c-ANCA, reacting with proteinase 3, is found in polyangiitis and Churg-Strauss syndrome; p-ANCA, reacting with myeloperoxidase is found in Wegener granulomatosis.
Farlex Partner Medical Dictionary © Farlex 2012
References in periodicals archive ?
C3 and C4 levelswere decreased but the rest of the rheumatologic panel (anti-dsDNA, Anti-Ro, Anti-La, Anti-SM, Anti-RMP and antineutrophil cytoplasmic antibodies) was negative.
Antineutrophil cytoplasmic antibodies (ANCAs) to myeloperoxidase (MPO) and proteinase 3 (PR3) are associated with primary vasculitis affecting small- to medium-sized vessels.
Automation platforms with harmonized software and hardware components have in recent years contributed enormously to the standardization and simplification of the evaluation process, especially for ANA, but also antineutrophil cytoplasmic antibodies (ANCA) and Crithidia luciliae immunofluorescence test (CLIFT).
Objective: To explore clinical and laboratory features, therapy and outcome of antineutrophil cytoplasmic antibodies (ANCA) associated vasculitis (AAV) patients from our tertiary care center.
Negative test results were obtained for hepatitis-B surface antigen, hepatitis C antibody, antimitochondrial antibody, antinuclear antibody, rheumatoid factor, antineutrophil cytoplasmic antibodies, and quantiferon for tuberculosis.
Tubiana et al., "Prevalence of Antineutrophil Cytoplasmic Antibodies in Infective Endocarditis," Arthritis & Rheumatology, vol.
Sebastiani et al., "Antineutrophil cytoplasmic antibodies in 566 European patients with systemic lupus erythematosus: prevalence, clinical associations and correlation with other autoantibodies.
Numerous autoantibodies are associated with both SLE and LN to include antineutrophil cytoplasmic antibodies (ANCA) [4, 5].
Antineutrophil cytoplasmic antibodies of IgA class in neutrophilic dermatoses with emphasis on erythema elevatum diutinum.
She'd also tested positive for cytoplasmic antineutrophil cytoplasmic antibodies (c-ANCA), antinuclear antibodies (ANA), anti-double stranded DNA (anti-dsDNA), and anticardiolipin IgM.
Other immunologic tests (antidouble strand DNA, antinuclear antibodies, antineutrophil cytoplasmic antibodies, proliferating cell nuclear antigen, and human leukocyte antigen B27) were all negative.
Albert et al., "Intravenous immunoglobulins contain naturally occurring antibodies that mimic antineutrophil cytoplasmic antibodies and activate neutrophils in a TNF[alpha]-dependent and Fc-receptor-independent way," Blood, vol.